Association between functional neurometry test results and blood biomarkers indicative of anaemia, subclinical inflammation, and endothelial dysfunction

Abstract

Introduction: Functional neurometry-FN assesses the functioning of the autonomic nervous system. Objective: The association between FN test results and the biomarkers of anaemia, subclinical inflammation-SI and endothelial dysfunction-ED was evaluated. Method: 412 male patients aged between 18-50 years were evaluated by FN and Laboratory Testing. Groups: control (CONT, n=194) and dysfunctional (DYSF, n=218). FN categories: Anxiety Control-(AC) ≥75%, Baroreflex Index-(BRI) ≥90%, Hemodynamic- (HD) ≤10% and Physiological response-(PR) =31.5 o -32.5 o , expressed in Median/ (Minimum-Maximum). Biomarkers: red blood cells-RBC, haemoglobin, haematocrit, mean corpuscular volume-MCV; mean corpuscular haemoglobin-MCH; mean corpuscular haemoglobin concentration-MCHC; red cell distribution width-RDW; total leukocytes-TL, ferritin, transferrin saturation-TS, B12, homocysteine, C-reactive protein-CRP; fibrinogen; 25-hydroxy-vitamin-D3; apolipoprotein A1-Apo-A1; apolipoprotein B-Apo-B; glutamic oxalacetic transaminase-GOT; glutamic-pyruvic transaminase-GPT; Gamma GT; 8am cortisol; IgE; total cholesterol-TC; triglycerides-TG, and; high-density lipoprotein-HDL and low-density lipoprotein-LDL, expressed in frequency-[percentage] and analysed by the Chi-square test with p≤0.05*. Results: DYSF presented: AC=24.91/(10.11-69.17), Conclusion: This study found a significant association between FN test results and biomarkers indicative of anaemia, SI and ED.