CHEMOTHERAPY OF LEPROSY

G. Faget, P. Erickson
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引用次数: 10

Abstract

Early in 1941 a new drug, "promin," was introduced in the treatment of leprosy at the National Leprosarium. After several months' treatment of a few patients with this drug rather decided improvement occurred in their specific leprous lesions. In November 1943 the "promin" treatment of leprosy was first reported in the medical literature 1 and was regarded as the most encouraging experimental treatment ever undertaken at the National Leprosarium. Since then "promin" and its related sulfones, "diasone" and "promizole," have been used extensively in the treatment of leprosy with exceedingly good results. At the Second Pan-American Leprosy Conference held in Rio de Janeiro, Brazil, in October 1946, the Subcommittee on Therapeutics took cognizance of the divergent opinions on the effect of chaulmoogra oil and its derivatives in the treatment of leprosy. 2 The committee advised that the efficacy of chaulmoogra oil be reevaluated. Simultaneously, it recognized the sulfone drugs as
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麻风病化疗
早在1941年,一种名为“普罗明”的新药被引入国家麻风医院,用于治疗麻风病。经过几个月的治疗,一些病人用这种药物相当明显的改善发生在他们的特定麻风病变。1943年11月,医学文献首次报道了麻风病的“promin”治疗方法,并被认为是国家麻风病医院进行过的最令人鼓舞的实验性治疗方法。从那时起,“普罗明”和与之相关的磺胺类药物“阿索酮”和“普罗佐尔”被广泛用于治疗麻风病,并取得了非常好的效果。1946年10月,在巴西里约热内卢举行的第二届泛美麻风病会议上,治疗学小组委员会注意到关于沙豆油及其衍生物在麻风病治疗中的作用的不同意见。2 .委员会建议重新评价黄芩油的功效。同时,它识别出砜类药物为
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