Structural components of chemosensory protein mutations in the silkworm moth, Bombyx mori

Q1 Agricultural and Biological Sciences Agri Gene Pub Date : 2016-12-01 DOI:10.1016/j.aggene.2016.08.006
Ning Xuan , Balaji Rajashekar , Sergo Kasvandik , Jean-François Picimbon
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引用次数: 16

Abstract

The letter addresses the contribution of RNA editing to tissue-specific diversification of insect chemosensory proteins (CSPs) with a particular focus on the moth Bombyx mori. This narrow focus on RNA editing of a single gene family in a single insect species might have a broad significance to an integrated view of protein structure evolution. Including protein structure models of new edited variants and mapping the position of specific cysteine and glycine residues believed to be inserted though or mediated via mutation, we suggest effects of RNA editing on CSP protein function.

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家蚕化学感觉蛋白突变的结构成分
这封信讨论了RNA编辑对昆虫化学感觉蛋白(csp)组织特异性多样化的贡献,特别关注了家蚕。这种对单一昆虫物种中单个基因家族的RNA编辑的狭隘关注可能对蛋白质结构进化的综合观点具有广泛的意义。包括新编辑变体的蛋白质结构模型,以及被认为通过突变插入或通过突变介导的特定半胱氨酸和甘氨酸残基的定位,我们提出RNA编辑对CSP蛋白功能的影响。
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Agri Gene
Agri Gene Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)
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期刊介绍: Agri Gene publishes papers that focus on the regulation, expression, function and evolution of genes in crop plants, farm animals, and agriculturally important insects and microorganisms. Agri Gene strives to be a diverse journal and topics in multiple fields will be considered for publication so long as their main focus is on agriculturally important organisms (plants, animals, insects, or microorganisms). Although not limited to the following, some examples of potential topics include: Gene discovery and characterization. Genetic markers to guide traditional breeding. Genetic effects of transposable elements. Evolutionary genetics, molecular evolution, population genetics, and phylogenetics. Profiling of gene expression and genetic variation. Biotechnology and crop or livestock improvement. Genetic improvement of biological control microorganisms. Genetic control of secondary metabolic pathways and metabolic enzymes of crop pathogens. Transcription analysis of beneficial or pest insect developmental stages Agri Gene encourages submission of novel manuscripts that present a reasonable level of analysis, functional relevance and/or mechanistic insight. Agri Gene also welcomes papers that have predominantly a descriptive component but improve the essential basis of knowledge for subsequent functional studies, or which provide important confirmation of recently published discoveries provided that the information is new.
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