Initial chest CT imaging features of COVID-19 and their relation to clinical types

N. Fan, W. Yang, Y. Liang, W. Fan
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Abstract

Objective: To investigate the initial chest CT imaging features and clinical types of patients with COVID-19. Methods: A total 165 patients with COVID-19 were retrospectively analyzed according to different age groups and different clinical classifications. Results: There were statistically significant differences in involvement sites, involvement range, lesion distribution and largest diameter of the lesions in COVID-19 patients among different age groups. Logistic regression analysis of age between normal type group and severe type group showed statistical significance (P<0.05). The maximum sensitivity and specificity were 64.20% and 69.00%. The corresponding age threshold was 50.5 years old. Conclusion: The main manifestations of initial chest CT in COVID-19 patients were ground-glass opacities, most often involving the posterior basal segment of the lower lung. Single site involvement was more common in 17-35 years patients. Most of the lesions were distributed around the subpleural and bronchovascular bundle in 36-90 years patients, involving both lungs and reaching more than two pulmonary lobes. For the COVID-19 patients with diabetes, hypertension, or older than 50.5 years, early diagnosis, isolation and treatment are necessary, and the changes of their conditions should be closely mornitored. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.
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新型冠状病毒肺炎胸部CT首发表现及其与临床分型的关系
目的:探讨新型冠状病毒肺炎(COVID-19)患者的早期胸部CT影像特征及临床分型。方法:对165例新冠肺炎患者按不同年龄组、不同临床分型进行回顾性分析。结果:不同年龄组COVID-19患者的受累部位、受累范围、病变分布、病变最大直径等差异均有统计学意义。正常型组与重度型组年龄差异Logistic回归分析,差异有统计学意义(P<0.05)。灵敏度和特异度分别为64.20%和69.00%。相应的年龄阈值为50.5岁。结论:新冠肺炎患者初始胸部CT表现以磨玻璃影为主,多累及下肺后基段。单部位受累在17-35岁的患者中更为常见。36-90岁患者多分布于胸膜下及支气管维管束周围,累及双肺,累及两个以上肺叶。对合并糖尿病、高血压及年龄大于50.5岁的新冠肺炎患者,应早诊断、早隔离、早治疗,密切监测病情变化。©2021,武汉大学医学杂志编辑委员会。版权所有。
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来源期刊
武汉大学学报(医学版)
武汉大学学报(医学版) Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
7289
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