{"title":"TRAB Measurements: Ready for Prime Time?","authors":"C. Lau, T. Aw","doi":"10.16966/2380-548x.157","DOIUrl":null,"url":null,"abstract":"generation TRAb assays. Tozzoli R, et al. [7] compared an automated 3rd generation TRAb (RAD 120; Radim, Pomezia, Italy) against a second 2nd generation TRAb immunoassay (Lumitest TRAK human; Brahms, Berlin, Germany). The ROC plot of the 3rd generation assay was excellent (AUC 0.994), with a lower optimal threshold of 1.25 U/L compared to second generation value of 1.99 U/l. The 3rd generation assay had a higher sensitivity of 97.6% versus 95.1% for the 2nd generation assay. The 3rd generation assay also had greater analytical precision with a faster turnaround time.","PeriodicalId":73446,"journal":{"name":"International journal of endocrinology and metabolic disorders","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of endocrinology and metabolic disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.16966/2380-548x.157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
generation TRAb assays. Tozzoli R, et al. [7] compared an automated 3rd generation TRAb (RAD 120; Radim, Pomezia, Italy) against a second 2nd generation TRAb immunoassay (Lumitest TRAK human; Brahms, Berlin, Germany). The ROC plot of the 3rd generation assay was excellent (AUC 0.994), with a lower optimal threshold of 1.25 U/L compared to second generation value of 1.99 U/l. The 3rd generation assay had a higher sensitivity of 97.6% versus 95.1% for the 2nd generation assay. The 3rd generation assay also had greater analytical precision with a faster turnaround time.