N. Shapovalova, V. Novikova, E. Yablokova, E. Loshkova, M. I. Erokhina, E. V. Chibrina, E. Kondratyeva, A. Khavkin
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引用次数: 0
Abstract
The aim of this review was to highlight current approaches to the diagnosis of non-celiac gluten sensitivity. A literature search was performed in PubMed, NCBI (National Library of Medicine), Scopus, and Embase databases using the following key words: “non-celiac gluten sensitivity”, “non-celiac wheat sensitivity” combined with “diagnostics”, “biomarkers”. The selection criteria used were English, human research, and clinical trials. Only articles published in peer-reviewed journals were included in the study. The disadvantages of the currently available diagnostic protocol, a double-blind, placebo-controlled study, were presented, among them the difficulties of differential diagnosis in the first step and the problems of gluten provocation in the second. Potential biomarkers were introduced, the determination of which may eventually become an alternative to the current approach. Key words: celiac disease, gluten intolerance, non-celiac gluten sensitivity, wheat allergy, gluten
本综述的目的是强调目前诊断非乳糜泻麸质敏感性的方法。在PubMed、NCBI (National Library of Medicine)、Scopus和Embase数据库中检索相关文献，检索关键词为:“非乳糜泻麸质敏感性”、“非乳糜泻小麦敏感性”结合“诊断”、“生物标志物”。选择标准为英语、人体研究和临床试验。只有发表在同行评议期刊上的文章被纳入研究。目前可用的诊断方案，双盲，安慰剂对照研究的缺点，其中包括在第一步鉴别诊断的困难和在第二步麸质激发的问题。介绍了潜在的生物标志物，确定哪些可能最终成为当前方法的替代方法。关键词:乳糜泻，麸质不耐症，非麸质敏感，小麦过敏，麸质
期刊介绍：
The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.
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