Rheological characterization of thermal phase behavior of anionic lipid DMPG dispersions

Q4 Engineering Journal of Biorheology Pub Date : 2017-01-01 DOI:10.17106/JBR.31.6
S. Fujii
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引用次数: 2

Abstract

We study thermo-structural behavior of anionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) dispersed systems. Continuous chain-melting transition of DMPG induces anomalous intermediate phase between gel and fluid phases. We found that the intermediate phase can be divided into two domains; anisotropic phase with high orientational order and isotropic viscous phase. Anisotropic phase would be identified to perforated lamellae or bicelle formed by rupturing the perforated vesicles under shear. Isotropic viscous phase, on the other hand, might be identified to densely packed perforated vesicle dispersions formed by rearranging extended bilayer membranes.
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阴离子脂质DMPG分散体热相行为的流变学表征
我们研究了阴离子脂质1,2-二肉豆醇-sn-甘油-3-磷酸甘油(DMPG)分散体系的热结构行为。DMPG的连续链熔转变在凝胶相和流体相之间产生了异常中间相。我们发现中间阶段可以分为两个区域;具有高取向序的各向异性相和各向同性粘性相。各向异性相可识别为在剪切作用下穿孔囊泡破裂形成的穿孔片或小柱。另一方面,各向同性粘性相可能是由扩展的双层膜重新排列而形成的密集排列的穿孔囊泡分散体。
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来源期刊
Journal of Biorheology
Journal of Biorheology Engineering-Mechanical Engineering
CiteScore
0.50
自引率
0.00%
发文量
5
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