Historical overview and future perspective of the percutaneous coronary intervention with special emphasis on the development of coronary stent

Q4 Engineering Journal of Biorheology Pub Date : 2022-01-01 DOI:10.17106/jbr.36.23
G. Nakaji, Maroka Shinchi, Y. Ohba, A. Koike
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Abstract

Percutaneous coronary intervention (PCI) using balloon technology and stent implantation has revolutionized the interventional cardiology since the late 1970s. The plane old balloon angioplasty (POBA) was first proposed in the late 1970s as an alternative to coronary artery bypass grafting (CABG) for the treatment of coronary artery disease (CAD) such as angina pectoris and acute myocardial infarction (AMI). Thereafter, bare metal stent (BMS) was designed to overcome the problems proposed by POBA such as acute occlusion and restenosis of coronary target lesion. However, a new problem of BMS-induced in-stent restenosis (ISR) has appeared, and drug-eluting stent (DES) was introduced to resolve the problem of ISR. DES has improved the clinical outcome of patients undergoing PCI. Contemporary stent technology shows remarkable progress, and further effort continues to improve the design, structure, and materials of DES. However, DES has proposed a new problem of very late stent thrombosis. To overcome this late complication, non-stent strategy is introduced into the PCI. This article aims to review the historical development and future perspective of the PCI especially focusing on the evolution of DES.
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经皮冠状动脉介入治疗的历史回顾和未来展望,重点介绍冠状动脉支架的发展
自20世纪70年代末以来,使用球囊技术和支架植入的经皮冠状动脉介入治疗(PCI)彻底改变了介入心脏病学。平面旧球囊血管成形术(POBA)于20世纪70年代末首次提出,作为冠状动脉旁路移植术(CABG)的替代方案,用于治疗冠心病(CAD),如心绞痛和急性心肌梗死(AMI)。因此,裸金属支架(bare metal stent, BMS)的设计克服了POBA带来的冠状动脉靶病变急性闭塞、再狭窄等问题。然而,bms诱导支架内再狭窄(ISR)的新问题已经出现,药物洗脱支架(DES)的引入解决了ISR问题。DES改善了PCI患者的临床预后。当代支架技术取得了显著的进步,DES的设计、结构和材料不断得到改进,但DES也提出了一个新的问题,即非常晚期的支架血栓形成。为了克服这种晚期并发症,PCI引入了非支架策略。本文旨在回顾PCI的历史发展和未来前景,特别是关注DES的发展。
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来源期刊
Journal of Biorheology
Journal of Biorheology Engineering-Mechanical Engineering
CiteScore
0.50
自引率
0.00%
发文量
5
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