CHRONIC HEPATITIS C IN THE RUSSIAN FEDERATION AFTER STARTING THE HCV ELIMINATION PROGRAM

A. A. Dzemova, R. Ganchenko, G. Trifonova, E. Esaulenko
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引用次数: 1

Abstract

Background. Five years have passed since the adoption of the strategy for the elimination of viral hepatitis. It is necessary to take stock of the frst results. Objective – to assess the dynamics of the epidemic process of CHC and the clinical manifestations of the disease during the period of 2015-2019. Material and methods. The article analyzes the data from the state statistical reporting of infectious diseases in the Russian Federation (RF), from the reference-center for the monitoring of viral hepatitis, from statistical tables compiled at Methodological and Research Center for Epidemiological Surveillance of Viral Hepatitis under Pasteur Institute of Epidemiology and Microbiology. The data from the Federal register of patients with viral hepatitis were used. The article analyzes our own experience of observing 555 patients with HCV at different stages of the disease. Results. In 2015–2019, CHC incidence in the RF decreased by 20% (30,90/0000- in 2019, 38,00/0000– in 2015). The total number of people with CHC is increasing (in 2015 – 562 622 people, in 2019 – 635372). It is estimated that only 20% of those infected are under surveillance. The death rate from CHC remains high. The proportion of patients with an advanced stage of CHC is about 20%. The proportion of decompensated cirrhosis decreased by 8%. In recent years, government funding for the treatment has increased, but only about 8% of all registered CHC patients are covered by the therapy. Conclusions. In the RF the WHO strategy targets have not been achieved by 2020. That’s why it’s important to develop a strategy to counter the spread of HCV for the period up to 2030.
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俄罗斯联邦在启动HCV消除计划后的慢性丙型肝炎
背景。自通过消除病毒性肝炎战略以来,已经过去了五年。有必要对最初的结果进行评估。目的:了解2015-2019年CHC流行动态及临床表现。材料和方法。本文分析了俄罗斯联邦传染病国家统计报告的数据、病毒性肝炎监测参考中心的数据、巴斯德流行病学和微生物学研究所病毒性肝炎流行病学监测方法和研究中心编制的统计表。数据来自病毒性肝炎患者联邦登记册。本文分析了我们对555例不同阶段HCV患者的观察经验。结果。2015 - 2019年,RF的CHC发病率下降了20%(2019年为30,90/0000,2015年为38,000 /0000)。CHC的总人数正在增加(2015年为562 622人,2019年为635372人)。据估计,只有20%的感染者受到监测。CHC的死亡率仍然很高。晚期CHC患者比例约为20%。失代偿性肝硬化比例下降8%。近年来,政府对这种治疗的资助有所增加,但在所有登记的CHC患者中,只有约8%的人接受了这种治疗。结论。在RF中,世卫组织的战略目标到2020年尚未实现。这就是为什么必须制定一项战略,在2030年之前遏制丙型肝炎病毒的传播。
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