Chronic Myelogenous Leukemia in Humans

Abstract

Chronic myelogenous leukemia (CML), also referred to as chronic myelocytic leukemia, may be a cancer of the white blood cells. It’s a sort of leukemia characterized by the increased and unregulated growth of myeloid cells within the bone marrow and therefore the accumulation of those cells within the blood. CML may be a clonal bone marrow somatic cell disorder during which a proliferation of mature granulocytes (neutrophils, eosinophils and basophils) and their precursors is found. it's a kind of myeloproliferative neoplasm related to a characteristic chromosomal translocation called the Philadelphia chromosome.