Carcinoma Ovary with Lung Metastasis: A Rare Case Report

S. Sonvane
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Abstract

Ovarian cancer is the most lethal gynecological malignancy. Despite advances in chemotherapy, five year survival rate of advanced ovarian cancer patients with peritoneal metastasis remains around 30%. The most significant prognostic factor is stage and most patients present at an advanced stage with peritoneal dissemination. There is often no clearly identifiable precursor lesion, therefore, the events leading to metastatic disease are poorly understood. Solitary lung metastasis is extremely rare. We report the case of a 39-year-old woman who was admitted to our department with a lung mass. She had a past history of ovarian cancer 6years ago for which she underwent Cytoreductive surgery and HIPEC in august 2016. Histopathology report suggestive of High-grade serous carcinoma. She received adjuvant chemotherapy. She was on follow up and PET scan shows two soft tissue density nodules noted in left lung lower lobe largest 2.8×2.5cm. Left lower lobectomy was performed. Microscopically, the tumor was a high-grade serous carcinoma and was diagnosed as an ovarian cancer metastasis.
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卵巢癌合并肺转移1例报告
卵巢癌是最致命的妇科恶性肿瘤。尽管化疗取得了进展,但晚期卵巢癌腹膜转移患者的5年生存率仍在30%左右。最重要的预后因素是分期,大多数患者出现在腹膜播散的晚期。通常没有明确识别的前体病变,因此,导致转移性疾病的事件知之甚少。孤立性肺转移极为罕见。我们报告一位39岁的女性,因肺部肿块住进我科。6年前有卵巢癌病史,2016年8月接受了细胞减少手术和HIPEC。组织病理学报告提示高级别浆液性癌。她接受了辅助化疗。她接受了随访,PET扫描显示左肺下叶两个软组织密度结节,最大2.8×2.5cm。行左下叶切除术。显微镜下,肿瘤为高级别浆液性癌,诊断为卵巢癌转移。
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