Bloodstream Infection in the Paediatric Cancer Patients: Bacteriological Profile and Drug Resistance Patterns in Shenzhen, China

Sandip Patil, B. Lopes, Hongyu Chen, Lian Ma, Feiqiu Wen
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Abstract

Bloodstream Infections (BSI) remain a main cause of death in pediatric cancer patients. We present the first report on the microbiological profile of bacteremia and drug resistance patterns in Shenzhen, China. We examined the types of bloodstream infectious agents and their antimicrobial susceptibility pattern in the pediatric oncology patients, from Shenzhen Children’s Hospital from January 2016 to October 2018. Acinetobacter baumannii (12.82%), Klebsiella pneumoniae (12.82%) and Staphylococcus epidermidis (34.61%) were highly prevalent in cancer patients with bloodstream infection. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae were also predominant. 29% of isolates were resistant to more than two class of antibiotics so call them as multi-drug resistant isolates.
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中国深圳儿童癌症患者血液感染的细菌学特征和耐药模式
血液感染(BSI)仍然是儿童癌症患者死亡的主要原因。我们首次报道了中国深圳菌血症和耐药模式的微生物学概况。我们检测了2016年1月至2018年10月深圳儿童医院儿科肿瘤患者血液感染因子的类型及其抗菌药物敏感性模式。血液感染的癌症患者中鲍曼不动杆菌(12.82%)、肺炎克雷伯菌(12.82%)和表皮葡萄球菌(34.61%)高发。广谱产β -内酰胺酶的大肠杆菌和肺炎克雷伯菌也占优势。29%的分离株对两类以上抗生素具有耐药性,因此称之为多重耐药分离株。
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