Detection of Mycoplasma pneumoniae in Hospitalized Patients with Respiratory Tract Infection in Marrakech 2018

N. Daoudi, A. Rabi, G. Draiss, N. Rada, M. Bouskraoui, M. Youssef, Younous Said, F. Bennaoui, Nadia El idrissi Sliline, Fadl Mrabih Rabou Maouainine, N. Soraa
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Abstract

Background: Mycoplasma pneumoniae (M. pneumoniae) is a commonly causative pathogen for Respiratory Tract Infections (RTIs) in humans. The aim of this study was to assess the prevalence of Mycoplasma pneumoniae infection in children and adult with RTIs and clinical, radiological features. Methods: We retrospectively analyzed the clinical data of 338 consecutive RTIs patients (children and adults) who visited a teaching hospital from January to December 2018. M. pneumoniae was detected by real-time multiplex PCR in nasopharyngeal aspirates. Results: Mycoplasma pneumoniae pneumonia was diagnosed in 3.55% of all respiratory tract infection investigated. The median (IQR) age was 6.48 years (range from 14 days to 36 years), most of the patients were children with clinical symptoms of RTIs (11/12). A cough (100%) and fever (66.66%) were more frequent symptoms observed in patients with Mycoplasma pneumoniae infection. Conclusion: M. pneumoniae is a significant cause of LRTI in children and adult but still not a major respiratory pathogen with a low rate in Morocco and cause infection difficult to distinguish from a respiratory infection caused by other respiratory pathogens.
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2018年马拉喀什地区住院呼吸道感染患者肺炎支原体检测结果分析
背景:肺炎支原体(M. pneumoniae)是人类呼吸道感染(RTIs)的常见病原体。本研究的目的是评估呼吸道感染的儿童和成人肺炎支原体感染的患病率和临床、影像学特征。方法:回顾性分析2018年1月至12月在某教学医院连续就诊的338例RTIs患者(儿童和成人)的临床资料。采用实时多重PCR检测鼻咽吸出物中肺炎支原体。结果:肺炎支原体肺炎占所有呼吸道感染的3.55%。中位(IQR)年龄为6.48岁(范围为14天至36岁),大多数患者为具有RTIs临床症状的儿童(11/12)。肺炎支原体感染患者以咳嗽(100%)和发热(66.66%)为主。结论:肺炎支原体是摩洛哥儿童和成人下呼吸道感染的重要病因,但仍不是主要的呼吸道病原体,发病率较低,且与其他呼吸道病原体引起的呼吸道感染难以区分。
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