ACUTE PANCREATITIS OF BILIARY ETIOLOGY. Report 1. EPIDEMIOLOGY AND CURRENT VIEWS ON PATHOGENESIS

Abstract

The epidemiological data and modern ideas concerning the pathogenesis of acute biliary pancreatitis are presented. Acute pancreatitis of biliary etiology is a widespread pathology with the lethality rate of 2–7%, and at a severe course – 17–39%. The leading pathogenetic mechanism of acute pancreatitis of biliary etiology is pancreaticobiliary ductal hypertesion. During the conservative treatment the relapse rate of acute biliary pancreatitis reaches 90% with the lethality rate up to 31%. The only risk factor of the relapse development is refusal to perform cholecystectomy after the first attack of acute biliary pancreatitis to the patients whose condition permitted to survive the intervention.