CURRENT STATIN POSITIONS IN THE PREVENTION OF CARDIOVASCULAR EVENTS

Bova A. A., Gromova Y. M.
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Abstract

Progression of the atherosclerotic process with the development of clinical manifestations is associated with an increased level of atherogenic fractions of lipids, primarily low-density lipoprotein cholesterol. The most studied group of lipid lowering drugs, which have proven their effectiveness in reducing cardiovascular morbidity and mortality, and the first choice drugs in the treatment of dyslipidemia are statins. The updated international guidelines for the treatment of dyslipidemia revised approaches to cardiovascular risk stratification and lipid lowering therapy tactics in different patient cohorts.
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目前他汀类药物在预防心血管事件中的地位
随着临床表现的发展,动脉粥样硬化过程的进展与导致动脉粥样硬化的脂质组分(主要是低密度脂蛋白胆固醇)水平的增加有关。他汀类药物是研究最多的一类降脂药物,已证明其降低心血管疾病发病率和死亡率的有效性,是治疗血脂异常的首选药物。最新的国际血脂异常治疗指南修订了不同患者群体的心血管风险分层方法和降脂治疗策略。
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