Random Forest of Interaction Trees for Estimating Individualized Treatment Regimes with Ordered Treatment Levels in Observational Studies

Justine Thorp, R. Levine, Luo Li, J. Fan
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引用次数: 2

Abstract

Traditional methods for evaluating a potential treatment have focused on the average treatment effect. However, there exist situations where individuals can experience significantly heterogeneous responses to a treatment. In these situations, one needs to account for the differences among individuals when estimating the treatment effect. Li et al. (2022) proposed a method based on random forest of interaction trees (RFIT) for a binary or categorical treatment variable, while incorporating the propensity score in the construction of random forest. Motivated by the need to evaluate the effect of tutoring sessions at a Math and Stat Learning Center (MSLC), we extend their approach to an ordinal treatment variable. Our approach improves upon RFIT for multiple treatments by incorporating the ordered structure of the treatment variable into the tree growing process. To illustrate the effectiveness of our proposed method, we conduct simulation studies where the results show that our proposed method has a lower mean squared error and higher optimal treatment classification, and is able to identify the most important variables that impact the treatment effect. We then apply the proposed method to estimate how the number of visits to the MSLC impacts an individual student’s probability of passing an introductory statistics course. Our results show that every student is recommended to go to the MSLC at least once and some can drastically improve their chance of passing the course by going the optimal number of times suggested by our analysis.
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在观察性研究中估计有顺序治疗水平的个体化治疗方案的相互作用树随机森林
评估潜在治疗的传统方法侧重于平均治疗效果。然而,在某些情况下,个体可能会对一种治疗产生明显的异质反应。在这些情况下,在估计治疗效果时需要考虑到个体之间的差异。Li等人(2022)提出了一种基于相互作用树随机森林(RFIT)的方法,用于二元或分类处理变量,同时将倾向得分纳入随机森林的构建中。由于需要评估数学和统计学习中心(MSLC)辅导课程的效果,我们将他们的方法扩展到一个顺序处理变量。我们的方法通过将处理变量的有序结构纳入树木生长过程,改进了RFIT对多个处理的影响。为了说明我们提出的方法的有效性,我们进行了模拟研究,结果表明我们提出的方法具有较低的均方误差和较高的最优处理分类,并且能够识别影响处理效果的最重要变量。然后,我们应用所提出的方法来估计访问MSLC的次数如何影响单个学生通过入门统计课程的概率。我们的结果表明,每个学生都被建议至少去一次MSLC,有些学生可以通过我们的分析建议的最佳次数来大大提高他们通过课程的机会。
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