Comparision of Intubating Conditions at 60 Seconds with Different Doses of Rocuronium Using the Timing Principle

Abstract

Objective: To evaluate the intubating conditions with rocuronium at 0.6 mg/kg (2*ED 95) and 0.9 mg/kg (3*ED 95) at 60 s using the timing principle. Methods: 60 patients were divided into 2 groups of 30 each. Group A received 0.9 mg/kg and group B received 0.6 mg/kg of rocuronium. Intubation was done at 60 s. The Train of four monitoring was done at the adductor pollicis muscle. The TOF count at intubation and time to loss of TOF were noted and compared. Results: Intubating conditions were excellent 13 (65%) in group A compared to 9 (45%) in group B. The TOF count at intubation was not statistically significant (p=0.677) between the groups whereas time to loss of TOF (p=0.03) were significant between the groups. Conclusion: Clinically acceptable intubating conditions were found in both groups but the conditions were better with group A in comparision with group B.