Helmóz R. Appelt, J. S. Oliveira, R. Santos, O. Rodrigues, M. Z. Santos, E. Heck, L. C. Rosa
{"title":"Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety","authors":"Helmóz R. Appelt, J. S. Oliveira, R. Santos, O. Rodrigues, M. Z. Santos, E. Heck, L. C. Rosa","doi":"10.1155/2013/320892","DOIUrl":null,"url":null,"abstract":"A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.","PeriodicalId":13788,"journal":{"name":"International Journal of Carbohydrate Chemistry","volume":"2 1","pages":"1-5"},"PeriodicalIF":0.0000,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"17","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Carbohydrate Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2013/320892","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 17
Abstract
A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.