A New Generation of Glycoconjugated Azo Dyes Based on Aminosugars

L. Guazzelli, G. Catelani, F. D’Andrea
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Abstract

The third generation of glycoconjugated azo dyes (GADs) was prepared linking monoazo dyes to 6-amino-6-deoxy-d-galactose or 6′amino-6′-deoxylactose through mixed amido-ester connections. The complementary conjugation reactions were studied using the succinyl derivative of either the acetal protected aminosugar or the azo dye. Target “naturalized” GADs were obtained after acid hydrolysis of the acetal protecting groups present on the sugar moiety.
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基于氨基糖的新一代糖缀合偶氮染料
通过混合酰胺-酯连接,制备了第三代糖偶氮染料(GADs)。用缩醛保护的氨基糖或偶氮染料的琥珀酰衍生物研究了互补偶联反应。目标“自然化”GADs是通过酸水解糖部分上的缩醛保护基团得到的。
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