Social and Metabolic Risk Factors for Arterial Hypertension in Adolescents

Y. Kostyuchenko, T. Potupchik, L. Evert, E. Panicheva, Y. Dubrovsky, E. Usoltseva, N. Loseva
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Abstract

Aim: to study the features of social and metabolic indicators in adolescents with arterial hypertension (AH), to assess their informative significance and the magnitude of their contribution to the risk of developing this pathology. Design: a comparative clinical study of patients. Materials and Methods: The object of the study was adolescents aged 12–17 years (boys and girls) with and without AH. The 1st stage included the analysis of biomedical, social and metabolic indicators, the 2nd stage included an assessment of the informative significance and degree of participation of indicators as risk factors for AH. Methods: questioning, laboratory, clinical and functional, statistical. Examination program: verification of AH and its severity; association of AH with functional somatic disorders; features of biomedical, social and metabolic indicators; assessment of the significance and contribution of indicators as risk factors for AH. Results. Of the 504 examined, AH was diagnosed in 86 (17.06%) adolescents, of which 47.7% (41 people) had grade 1 AH and 52.3% (45 people) had grade 2 AH. Social risk factors for hypertension associated with family characteristics: the degree of marriage of parents — temporary cohabitation (OR = 3.36), father's profession — worker (OR = 3.14), father's education — secondary special (OR = 2.25), deviant family (OR = 2.78), family at medical and social risk (OR = 1.87). Metabolic predictors of the risk of AH: the presence of DLP (OR = 1.95), HChS (OR = 2.62), HTG (OR = 2.21), Hyper-β-CHS (OR = 1.87) and Hyper-pre-β-ChS (OR = 2.14). Conclusion. Along with traditional ones, it is necessary to identify and correct socially determined and metabolic risk factors for AH in order to optimize the diagnosis and prevention of this pathology in adolescents. Keywords: adolescents, arterial hypertension, risk factors, social factors, lipid spectrum
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青少年动脉高血压的社会和代谢危险因素
目的:研究青少年动脉性高血压(AH)的社会和代谢指标的特征,评估其信息意义及其对发生这种病理风险的贡献程度。设计:对患者进行比较临床研究。材料和方法:研究对象为12-17岁的青少年(男孩和女孩),有和没有AH。第一阶段包括生物医学、社会和代谢指标的分析,第二阶段包括指标作为AH危险因素的信息意义和参与程度的评估。方法:询问、实验室、临床、功能、统计。检查方案:AH及其严重程度的验证;AH与功能性躯体疾病的关系;生物医学、社会和代谢指标的特点;评估作为AH危险因素的指标的重要性和贡献。结果。在504名被检查的青少年中,86名(17.06%)被诊断为AH,其中47.7%(41人)为1级AH, 52.3%(45人)为2级AH。与家庭特征相关的高血压社会危险因素:父母婚姻程度-临时同居(OR = 3.36)、父亲职业-工人(OR = 3.14)、父亲教育程度-中等特殊(OR = 2.25)、异常家庭(OR = 2.78)、有医疗和社会风险家庭(OR = 1.87)。AH风险的代谢预测因子:DLP (OR = 1.95)、HChS (OR = 2.62)、HTG (OR = 2.21)、Hyper-β-CHS (OR = 1.87)和Hyper-pre -β-CHS (OR = 2.14)的存在。结论。除了传统的危险因素外,有必要识别和纠正AH的社会决定因素和代谢危险因素,以优化青少年AH的诊断和预防。关键词:青少年,高血压,危险因素,社会因素,血脂谱
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