New coronavirus infection in a child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia

S. M. Bezrodnova, N. A. Yatsenkо, G. M. Sirazhov, Yu. N. Kashina
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Abstract

Children are more likely to have asymptomatic and mild forms of novel coronavirus infection, as well as a more favorable outcome of the disease compared to adult patients. Children account for about 15% of all cases of COVID-19 recorded in the country. There are more and more reports of severe and even fatal cases of a new coronavirus infection in children. The development of severe forms of COVID-19 is typical for children at risk. Of particular interest are special groups of pediatric patients, such as children with immunodeficiencies of various etiologies.A clinical case of a new coronavirus infection with a fatal outcome in a 10-year-old child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia is presented.
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急性淋巴细胞白血病背景下与造血干细胞移植相关的严重继发性免疫缺陷儿童的新型冠状病毒感染
与成年患者相比,儿童更容易出现无症状和轻度的新型冠状病毒感染,也更有利于疾病的预后。儿童约占该国记录的所有COVID-19病例的15%。有越来越多的报道称,儿童感染新型冠状病毒的病例严重甚至致命。严重形式的COVID-19在高危儿童中很常见。特别感兴趣的是儿科患者的特殊群体,如各种病因的免疫缺陷儿童。一个新的冠状病毒感染的临床病例与致命的结果在一个10岁的儿童严重继发性免疫缺陷与造血干细胞移植在急性淋巴细胞白血病的背景下提出。
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