Histological types of polyps in large intestine biopsies; a single center experience

Parisa Masoum Zadeh, S. Ghorbani, M. Derakhshan
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Abstract

Introduction: Large intestine cancer is considered as one of the prevalent cancers among societies. Histological studies have shown that cancers in large intestine often originate from polyps from internal layer of the intestinal epithelial tissue. Objectives: The aim of this study was to investigate the types of polyps in large intestine biopsies in patients referring to Al-Zahra hospital in Iran. Patients and Methods: This is a cross-sectional study conducted on patients undergoing colonoscopy in 2014-2019. Characteristics of polyps were noted based on reports of colonoscopy and pathology. Results: In this study, 372 biopsies from patients aged between 10-96 years were analyzed. No significant difference was observed between two genders regarding location, size, histology, and morphology of polyps (P > 0.05). Adenomatous epithelial polyps are the most common types in all ages). Further analysis showed that most of the discovered polyps (23.3%) were in transverse colon. Conclusion: Adenomatous epithelial polyps are more frequent in patients because most of the discovered polyps were in transverse colon and most of them were adenomatous epithelial. These data were in line with the most of previous studies; however some paradoxical results were reported. More studies on larger populations should be performed.
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大肠息肉活检的组织学类型单中心体验
导读:大肠癌被认为是社会上常见的癌症之一。组织学研究表明,大肠肿瘤多起源于肠上皮组织内层的息肉。目的:本研究的目的是调查在伊朗Al-Zahra医院就诊的患者大肠活检中息肉的类型。患者和方法:这是一项针对2014-2019年结肠镜检查患者的横断面研究。息肉的特点是根据结肠镜检查和病理报告。结果:本研究分析了372例年龄在10-96岁之间的患者的活检。两性在息肉的位置、大小、组织学和形态上均无显著差异(P < 0.05)。腺瘤性上皮息肉是所有年龄段中最常见的类型)。进一步分析发现绝大多数息肉(23.3%)发生在横结肠。结论:腺瘤性上皮性息肉多见于横结肠,且以腺瘤性上皮性息肉居多。这些数据与之前的大多数研究一致;然而,报告了一些矛盾的结果。应该对更大的人口进行更多的研究。
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