A SUCCESSFUL PLATELET-RICH PLASMA TREATMENT IN A FAWN WITH OVER-MOTHERING WOUND IN THE PERINEAL AREA

Huan-Yu Hsu, N. Thongrueang, Guan‐Ming Ke, Hsu-Hsun Lee
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Abstract

Over-mothering syndrome is common in intensive deer farming; the wound is usually deep and hard to take care of, and results in neonatal mortality increased by bacterial infection related to the wound. Regenerate therapy might be an option for treating severe wounds due to over-mothering syndrome. Autologous platelet-rich plasma (PRP) is a widely used method to treat orthopedic issues in humans and animals. It contains several concentrated growth factors to promote tissue regeneration, without the complications of overreaction or of rejection issues. This report presents the successful treatment of autologous PRP in a fawn with a [Formula: see text][Formula: see text]cm wound in the perineal area, caused by an over-mothering doe. Autologous PRP was injected on both sides of the proximal of the gluteobiceps muscle and applied 3 times over the 20-day treatment period. The wound displayed rapid tissue regeneration with no complications. This successful application of PRP is the first report to enhance the regeneration of the vulva and the anus in a large animal. The PRP was injected on the proximal of the wound rather than directly on the wound to reduce potential irritation from physical contact to the wound, and the regeneration process was nice and fast. This protocol could provide clinical veterinarians with an effective and low labor cost method to treat severe and contaminated wounds in the perineal area.
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富血小板血浆治疗会阴区过度母性伤口的小鹿成功
过度母性综合症在集约化养鹿中很常见;伤口通常很深,难以护理,并且由于与伤口有关的细菌感染而导致新生儿死亡率增加。再生疗法可能是治疗由过度生育综合症引起的严重伤口的一种选择。自体富血小板血浆(PRP)是一种广泛应用于治疗人类和动物骨科问题的方法。它含有几种浓缩的生长因子,促进组织再生,没有过度反应或排斥问题的并发症。本报告介绍了自体PRP成功治疗由母鹿过度母性引起的会阴区域cm伤口的小鹿。自体PRP于臀大肌近端两侧注射,20天内应用3次。伤口组织再生迅速,无并发症。PRP的成功应用是首次报道在大型动物中促进外阴和肛门的再生。PRP注射在创面近端,而不是直接注射在创面上,以减少物理接触对创面的潜在刺激,并且再生过程良好且快速。该方案可为临床兽医治疗会阴区严重污染伤口提供一种有效且人工成本低的方法。
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