Pub Date : 2024-07-17DOI: 10.1142/s1682648524500057
Chun Chang, Chia-Yun Lu, I-Ying Chen, Hsien-Chi Wang
Ovariohysterectomy (OHE) is a common surgical procedure in small animals that causes significant postoperative pain. Tuning Element Relief Patches (TERPs) are silicone patches containing titanium salts, believed to relieve pain by resonating pain-related ion channels. In this experiment, 12 dogs undergoing OHE surgery received subcutaneous robenacoxib (group R, [Formula: see text]) injection or two sheets of TERPs (group T, [Formula: see text]) as postoperative analgesia to assess the analgesic effect of TERPs. The results demonstrated no significant differences in physiological parameters, pain scores and mechanical nociceptive thresholds (MNTs) between groups postoperatively, indicating that the TERPs provide comparable results to robenacoxib in managing postoperative pain in dogs undergoing OHE. While this study provides evidence of the pain-relieving effects of TERPs, further studies are required to evaluate their long-term safety and efficacy in various clinical conditions.
{"title":"EVALUATION OF THE POSTOPERATIVE ANALGESIC EFFECTS OF TUNING ELEMENT RELIEF PATCHES IN DOGS UNDERGOING OVARIOHYSTERECTOMY","authors":"Chun Chang, Chia-Yun Lu, I-Ying Chen, Hsien-Chi Wang","doi":"10.1142/s1682648524500057","DOIUrl":"https://doi.org/10.1142/s1682648524500057","url":null,"abstract":"Ovariohysterectomy (OHE) is a common surgical procedure in small animals that causes significant postoperative pain. Tuning Element Relief Patches (TERPs) are silicone patches containing titanium salts, believed to relieve pain by resonating pain-related ion channels. In this experiment, 12 dogs undergoing OHE surgery received subcutaneous robenacoxib (group R, [Formula: see text]) injection or two sheets of TERPs (group T, [Formula: see text]) as postoperative analgesia to assess the analgesic effect of TERPs. The results demonstrated no significant differences in physiological parameters, pain scores and mechanical nociceptive thresholds (MNTs) between groups postoperatively, indicating that the TERPs provide comparable results to robenacoxib in managing postoperative pain in dogs undergoing OHE. While this study provides evidence of the pain-relieving effects of TERPs, further studies are required to evaluate their long-term safety and efficacy in various clinical conditions.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-17DOI: 10.1142/s1682648524720053
Huan-Yu Hsu, Yu-Ching Chuang, Wei-Yu Hsu, Chih-Wei Huang, Guan-Ming Ke
An outbreak of a disease with multiple erosive papules and ulcers on the lips, noses, and tongues of calves was reported in Taiwan in August 2023. Five of 11 2–4-month-old dairy calves were affected. Oral swabs, nasal swabs, and esophageal–pharyngeal fluid were collected and tested positive for bovine papular stomatitis virus (BPSV) via quantitative real-time polymerase chain reaction assay (qPCR) for all of the affected calves. All of the positive calves remained positive for BPSV after 1 month of the outbreak, and the viral loads of the affected calves did not decrease within this period. To determine the genetic characteristics of this outbreak strain, phylogenetic analysis was performed with the partial B2L sequence of BPSV. The results revealed that the virus strain was closely related to isolates from Japan, the United States, and France. This is the first report on an outbreak in this particular region since 1988 and the first molecular characterization of BPSV in Taiwan.
{"title":"CASE REPORT: A SPORADIC BOVINE PAPULAR STOMATITIS VIRUS INFECTION IN DAIRY CALVES IN SOUTH TAIWAN","authors":"Huan-Yu Hsu, Yu-Ching Chuang, Wei-Yu Hsu, Chih-Wei Huang, Guan-Ming Ke","doi":"10.1142/s1682648524720053","DOIUrl":"https://doi.org/10.1142/s1682648524720053","url":null,"abstract":"An outbreak of a disease with multiple erosive papules and ulcers on the lips, noses, and tongues of calves was reported in Taiwan in August 2023. Five of 11 2–4-month-old dairy calves were affected. Oral swabs, nasal swabs, and esophageal–pharyngeal fluid were collected and tested positive for bovine papular stomatitis virus (BPSV) via quantitative real-time polymerase chain reaction assay (qPCR) for all of the affected calves. All of the positive calves remained positive for BPSV after 1 month of the outbreak, and the viral loads of the affected calves did not decrease within this period. To determine the genetic characteristics of this outbreak strain, phylogenetic analysis was performed with the partial B2L sequence of BPSV. The results revealed that the virus strain was closely related to isolates from Japan, the United States, and France. This is the first report on an outbreak in this particular region since 1988 and the first molecular characterization of BPSV in Taiwan.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-09DOI: 10.1142/s168264852450001x
Hyok Ryo, Yong-Mi Pyon, Hi-Pung Pak, Sun-Nam Pak
The renal cells were isolated from the kidney of different week-age of healthy rabbits by a single two-stage pass perfusion method and suspended in Hanks’ balanced salt solution (Ca[Formula: see text]-, Mg[Formula: see text]-free). The field strains of RHDV were inoculated into the suspension and incubated for 4 days at 37∘C. After incubation, the HA titer of each strain of RHDV in supernatant of virus growth was measured using human erythrocyte O type. There were differences in the HA titers of RHDV strains according to the renal cell of different week-age of rabbits, the number of hepatocyte, the strain of virus (RHDV-1, RHDV-2, RHDV-3) and the duration of incubation. The HA titer was highest when the virus was cultured in the renal cells isolated from more than 12 week-aged rabbits. And the HA titer of RHDV propagated in isolated renal cell was higher than hepatocytes. When immunized rabbits by inactivated virus strains (RHDV-1, RHDV-2 and RHDV-3), two strains, RHDV-1 and RHDV-3, showed the same level of HI titers with inactivated homogenate, but RHDV-2 did lower level of titer than the homogenate.
采用单次两段式灌流法从不同周龄的健康家兔肾脏中分离出肾细胞，并将其悬浮于 Hanks 平衡盐溶液（不含 Ca[式：见正文]，Mg[式：见正文]）中。将 RHDV 实地菌株接种到悬浮液中，在 37∘C 孵育 4 天。培养结束后，用人红细胞 O 型测定病毒生长上清液中各 RHDV 株系的 HA 滴度。不同周龄兔子的肾细胞、肝细胞数量、病毒株（RHDV-1、RHDV-2、RHDV-3）和培养时间对 RHDV 株系的 HA 滴度有差异。从 12 周龄以上的兔子分离的肾细胞培养病毒时，HA 滴度最高。在分离的肾细胞中繁殖的 RHDV 的 HA 滴度高于肝细胞。用灭活病毒株（RHDV-1、RHDV-2 和 RHDV-3）免疫兔子时，RHDV-1 和 RHDV-3 两株的 HI 滴度与灭活匀浆的滴度相同，但 RHDV-2 的滴度低于匀浆。
{"title":"CHARACTERISTICS FOR SOME RABBIT HEMORRHAGIC DISEASE VIRUS (RHDV) STRAINS PROPAGATED IN ISOLATED RENAL CELL OF RABBIT","authors":"Hyok Ryo, Yong-Mi Pyon, Hi-Pung Pak, Sun-Nam Pak","doi":"10.1142/s168264852450001x","DOIUrl":"https://doi.org/10.1142/s168264852450001x","url":null,"abstract":"The renal cells were isolated from the kidney of different week-age of healthy rabbits by a single two-stage pass perfusion method and suspended in Hanks’ balanced salt solution (Ca[Formula: see text]-, Mg[Formula: see text]-free). The field strains of RHDV were inoculated into the suspension and incubated for 4 days at 37∘C. After incubation, the HA titer of each strain of RHDV in supernatant of virus growth was measured using human erythrocyte O type. There were differences in the HA titers of RHDV strains according to the renal cell of different week-age of rabbits, the number of hepatocyte, the strain of virus (RHDV-1, RHDV-2, RHDV-3) and the duration of incubation. The HA titer was highest when the virus was cultured in the renal cells isolated from more than 12 week-aged rabbits. And the HA titer of RHDV propagated in isolated renal cell was higher than hepatocytes. When immunized rabbits by inactivated virus strains (RHDV-1, RHDV-2 and RHDV-3), two strains, RHDV-1 and RHDV-3, showed the same level of HI titers with inactivated homogenate, but RHDV-2 did lower level of titer than the homogenate.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-28DOI: 10.1142/s1682648524720028
Tzu-Yi Ma, Chih-Jung Kuo, Chih-Chung Chou, Pin-Chen Liu
A 11-month-old intact male Cavalier King Charles Spaniel (CKCS) dog was presented at the Teaching Hospital of National Chung Hsin University (NCHU-VMTH) due to thrombocytopenia without relevant clinical signs and no significant improvement after medication treatment. As per the complete blood profile, there was significant thrombocytopenia (platelet count 1–[Formula: see text] L) with mean platelet volume (MPV) ranging from 20.3 to 25.7[Formula: see text]fl. Tests for Babesia canis, B. gibsoni, Ehrlichia canis and Anaplasma phagocytophilum yielded negative results. Despite treatment with antibiotics and immunosuppressive drugs, the dog’s condition did not improve. The dog’s platelet morphology and absence of symptoms raised the suspicion of inherited macrothrombocytopenia. Genomic DNA sequencing analysis of the [Formula: see text]1-tubulin gene revealed a single-point mutation, specifically c.745[Formula: see text]G>A. This genetic analysis confirmed the presence of a [Formula: see text]1-tubulin mutation, marking the first reported case of such a mutation in a CKCS in Taiwan. Despite the diagnosis of this condition, both partial thromboplastin time (PTT) and active partial thromboplastin time (aPTT) were within normal ranges before neutering. When diagnosing the causes of thrombocytopenia in young patients, especially when there are no related clinical signs, it is crucial to consider prioritizing inherited macrothrombocytopenia, then thrombocytopenia secondary to parasite infection, or immune-mediated thrombocytopenia (IMT) to minimize unnecessary medication.
一只11个月大的完整雄性查理士王小猎犬（CKCS）因血小板减少症就诊于国立中兴大学教学医院（NCHU-VMTH），无相关临床症状，药物治疗后无明显改善。根据全血细胞分析，血小板明显减少（血小板计数为 1-[计算公式：见正文]L），平均血小板体积（MPV）为 20.3 至 25.7[计算公式：见正文]fl。犬巴贝斯虫、吉布森虫、犬埃立克虫和噬细胞嗜血杆菌的检测结果均为阴性。尽管使用了抗生素和免疫抑制剂，但该犬的病情并没有好转。从该犬的血小板形态和无症状来看，它被怀疑患有遗传性大血小板减少症。对[式中：见正文]1-tubulin 基因的基因组 DNA 测序分析发现了一个单点突变，具体为 c.745[式中：见正文]G>A。这项基因分析证实了[式：见正文]1-tubulin基因突变的存在，这也是台湾首例报告的CKCS基因突变病例。尽管诊断出了这种情况，但在绝育前，部分凝血活酶时间（PTT）和活性部分凝血活酶时间（aPTT）都在正常范围内。在诊断年轻患者血小板减少症的病因时，尤其是在没有相关临床症状时，必须优先考虑遗传性大血小板减少症，然后是继发于寄生虫感染的血小板减少症或免疫介导的血小板减少症（IMT），以尽量减少不必要的用药。
{"title":"CASE REPORT: INHERITED MACROTHROMBOCYTOPENIA IN A CAVALIER KING CHARLES SPANIEL","authors":"Tzu-Yi Ma, Chih-Jung Kuo, Chih-Chung Chou, Pin-Chen Liu","doi":"10.1142/s1682648524720028","DOIUrl":"https://doi.org/10.1142/s1682648524720028","url":null,"abstract":"A 11-month-old intact male Cavalier King Charles Spaniel (CKCS) dog was presented at the Teaching Hospital of National Chung Hsin University (NCHU-VMTH) due to thrombocytopenia without relevant clinical signs and no significant improvement after medication treatment. As per the complete blood profile, there was significant thrombocytopenia (platelet count 1–[Formula: see text] L) with mean platelet volume (MPV) ranging from 20.3 to 25.7[Formula: see text]fl. Tests for Babesia canis, B. gibsoni, Ehrlichia canis and Anaplasma phagocytophilum yielded negative results. Despite treatment with antibiotics and immunosuppressive drugs, the dog’s condition did not improve. The dog’s platelet morphology and absence of symptoms raised the suspicion of inherited macrothrombocytopenia. Genomic DNA sequencing analysis of the [Formula: see text]1-tubulin gene revealed a single-point mutation, specifically c.745[Formula: see text]G>A. This genetic analysis confirmed the presence of a [Formula: see text]1-tubulin mutation, marking the first reported case of such a mutation in a CKCS in Taiwan. Despite the diagnosis of this condition, both partial thromboplastin time (PTT) and active partial thromboplastin time (aPTT) were within normal ranges before neutering. When diagnosing the causes of thrombocytopenia in young patients, especially when there are no related clinical signs, it is crucial to consider prioritizing inherited macrothrombocytopenia, then thrombocytopenia secondary to parasite infection, or immune-mediated thrombocytopenia (IMT) to minimize unnecessary medication.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140420401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-16DOI: 10.1142/s1682648524300016
Haroon Afzal, Muhammad Umar, Waseem Hussain, Li-Ting Cheng
Lumpy skin disease (LSD) is a vector-borne disease of cattle and water buffalo caused by the lumpy skin disease virus (LSDV) of the Capripoxvirus genus. LSD mainly affects the skin and the lymphatics of animals, and manifests as firm skin nodules, low feed intake, and a drop in milk production. Animal-to-animal contact, blood-feeding insects, animal products, stable flies, and mosquitoes can facilitate the transmission of LSD across herds and borders. The first case of LSD was reported in 1929 in Zambia. It was endemic to Africa until 1985 and later spread to Eastern Europe and Asia. The latest outbreak of LSD was reported in the Asia-Pacific region. At present, biosafety measures (control of animal movement, vectors, and animal products) are being devised by authorities to tackle LSD. Vaccines are also being developed for LSDV in recent decades. Live attenuated vaccines of both homologous and heterologous (of the Capripoxvirus genus) virus strains were utilized. A few side effects of the live vaccines were observed, such as skin nodules, low feed intake, and a drop in milk production. Inactivated LSDV vaccines were produced, showing a higher safety profile than live vaccines, yet offering only partial protection and lacks cross-protection. Recombinant LSDV vaccines are also under development; however, challenges remain in terms of the best vaccine delivery methods and antigen selection from the large poxvirus genome. Overall, mass vaccination with an effective vaccine may play a central role in the control of LSDV.
{"title":"LUMPY SKIN DISEASE: AN ENCROACHING RISK IN CATTLE FARMING","authors":"Haroon Afzal, Muhammad Umar, Waseem Hussain, Li-Ting Cheng","doi":"10.1142/s1682648524300016","DOIUrl":"https://doi.org/10.1142/s1682648524300016","url":null,"abstract":"Lumpy skin disease (LSD) is a vector-borne disease of cattle and water buffalo caused by the lumpy skin disease virus (LSDV) of the Capripoxvirus genus. LSD mainly affects the skin and the lymphatics of animals, and manifests as firm skin nodules, low feed intake, and a drop in milk production. Animal-to-animal contact, blood-feeding insects, animal products, stable flies, and mosquitoes can facilitate the transmission of LSD across herds and borders. The first case of LSD was reported in 1929 in Zambia. It was endemic to Africa until 1985 and later spread to Eastern Europe and Asia. The latest outbreak of LSD was reported in the Asia-Pacific region. At present, biosafety measures (control of animal movement, vectors, and animal products) are being devised by authorities to tackle LSD. Vaccines are also being developed for LSDV in recent decades. Live attenuated vaccines of both homologous and heterologous (of the Capripoxvirus genus) virus strains were utilized. A few side effects of the live vaccines were observed, such as skin nodules, low feed intake, and a drop in milk production. Inactivated LSDV vaccines were produced, showing a higher safety profile than live vaccines, yet offering only partial protection and lacks cross-protection. Recombinant LSDV vaccines are also under development; however, challenges remain in terms of the best vaccine delivery methods and antigen selection from the large poxvirus genome. Overall, mass vaccination with an effective vaccine may play a central role in the control of LSDV.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139961261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-07DOI: 10.1142/s1682648524500033
M.S. See, Chih-Yu Lu, Hong-En Tsai, Tsung-Hsien Li, Chih Yao Chen, M.A. Tsai
This study reports on diseased Chelidonichthys spinosus fish that were originally obtained from the Taiwan Strait for exhibition in an aquarium. These fish showed abnormal swimming behavior, eye damage and skin lesions. Gross examination and histopathology revealed that the C. spinosus was suffering from severe nematode infections in the pyloric caeca, liver and mesentery. Marine nematodes from internal organs were verified by partially sequencing the internal transcribed spacer (ITS) gene. Sequencing results revealed that the nematodes shared 99.75% sequence identity with Raphidascaris lophii (GenBank accession No. MW132926). Additionally, secondary Vibrio harveyi infections were also detected in some C. spinosus. This is the first report of R. lophii infection in C. spinosus.
本研究报告的对象是最初从台湾海峡获得的用于水族馆展览的病鱼。这些鱼表现出异常的游泳行为、眼睛损伤和皮肤病变。经大体检查和组织病理学检查发现，刺鱼的幽门盲肠、肝脏和肠系膜受到严重的线虫感染。通过对内部转录间隔（ITS）基因进行部分测序，对来自内脏器官的海洋线虫进行了验证。测序结果显示，这些线虫与 Raphidascaris lophii（GenBank登录号：MW132926）的序列相同度为 99.75%。此外，在一些 C. spinosus 中还发现了继发性 Harveyi 弧菌感染。这是首次报道 C. spinosus 感染 R. lophii。
{"title":"FIRST REPORT OF RAPHIDASCARIS LOPHII INFECTION IN BLUEFIN SEAROBIN (CHELIDONICHTHYS SPINOSUS)","authors":"M.S. See, Chih-Yu Lu, Hong-En Tsai, Tsung-Hsien Li, Chih Yao Chen, M.A. Tsai","doi":"10.1142/s1682648524500033","DOIUrl":"https://doi.org/10.1142/s1682648524500033","url":null,"abstract":"This study reports on diseased Chelidonichthys spinosus fish that were originally obtained from the Taiwan Strait for exhibition in an aquarium. These fish showed abnormal swimming behavior, eye damage and skin lesions. Gross examination and histopathology revealed that the C. spinosus was suffering from severe nematode infections in the pyloric caeca, liver and mesentery. Marine nematodes from internal organs were verified by partially sequencing the internal transcribed spacer (ITS) gene. Sequencing results revealed that the nematodes shared 99.75% sequence identity with Raphidascaris lophii (GenBank accession No. MW132926). Additionally, secondary Vibrio harveyi infections were also detected in some C. spinosus. This is the first report of R. lophii infection in C. spinosus.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139965164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-25DOI: 10.1142/s1682648524720016
Kuei-Miao Chen, Ming-Pin Wu, Ting-Wei Chiu, Chien-Ning Hung, Jyhmirn Lai
Although salmonellosis has been considered an important problem in the ruminant farm from 10 weeks to 14 months old, there is no information about the disease in goats, especially in 2 to 3-day-old kids, in recent years. The goat farmers complained that the 2 to 3-day-old kids showed clinical signs of depression, weakness, lameness, and diarrhea. The kids might die within one week after the symptoms appeared. The mortality reached 60% (48/80). After many antimicrobial agents were dosed, no better outcome was expected. The farmer sent one kid to the official deputy for further investigation. By helping with bacterial and molecular biological techniques, autopsy, serotyping, and histopathological diagnosis, the kids were infected by Salmonella enterica subsp. enterica serovar Havana strain. After a farm visit, a moldy floor contaminated by 2 to 3[Formula: see text]cm thick feces was identified on the floor. After removing the mold and implementing disinfection, the outbreak was stopped. In conclusion, this report proves that salmonellosis has recently been identified in goat farms, especially in kids, within one week. Moreover, good hygiene and keeping feces out of barns are essential to preventing salmonellosis.
{"title":"CASE REPORT: POSSIBLE EMERGING OF SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR HAVANA INFECTION IN NEWBORN KID GOATS","authors":"Kuei-Miao Chen, Ming-Pin Wu, Ting-Wei Chiu, Chien-Ning Hung, Jyhmirn Lai","doi":"10.1142/s1682648524720016","DOIUrl":"https://doi.org/10.1142/s1682648524720016","url":null,"abstract":"Although salmonellosis has been considered an important problem in the ruminant farm from 10 weeks to 14 months old, there is no information about the disease in goats, especially in 2 to 3-day-old kids, in recent years. The goat farmers complained that the 2 to 3-day-old kids showed clinical signs of depression, weakness, lameness, and diarrhea. The kids might die within one week after the symptoms appeared. The mortality reached 60% (48/80). After many antimicrobial agents were dosed, no better outcome was expected. The farmer sent one kid to the official deputy for further investigation. By helping with bacterial and molecular biological techniques, autopsy, serotyping, and histopathological diagnosis, the kids were infected by Salmonella enterica subsp. enterica serovar Havana strain. After a farm visit, a moldy floor contaminated by 2 to 3[Formula: see text]cm thick feces was identified on the floor. After removing the mold and implementing disinfection, the outbreak was stopped. In conclusion, this report proves that salmonellosis has recently been identified in goat farms, especially in kids, within one week. Moreover, good hygiene and keeping feces out of barns are essential to preventing salmonellosis.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139596096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-18DOI: 10.1142/s1682648524500021
Chin-Chieh Yang, Wei-Hsiang Huang, Ya-Pei Chang
Image-guided stereotactic techniques can display the locations of surgical instruments and biopsy targets in real time, allowing minimally invasive brain biopsies with reduced risk. This study aimed to assess the accuracy of an optical frameless neuronavigation system in feline cadavers and describe potential influencing factors. Phantom lesions were created in different brain regions and depths in 15 feline cadavers. After installing eight fiducial markers in the frontal bone and zygomatic arches, magnetic resonance imaging (MRI) was performed, and the images were imported into the neuronavigation system. Following patient and instrument registration, diluted gadolinium was injected into the phantom lesion (target), guided by the neuronavigation system. The coordinates of the target and contrast points were determined on repeated MRI scans and the distance between them was defined as the targeting error. The time from target selection to the completion of gadolinium injection was recorded as the required time. The targeting error and required time were compared between the initial 30% and final 30% of the collected data to assess the influence of operator experience. Among 76 lesions, the mean targeting error was [Formula: see text][Formula: see text]mm (95% confidence interval 2.76–3.15[Formula: see text]mm). Lesion location, lesion depth, and operator experience did not affect the accuracy; however, operator experience reduced the required time. This frameless optical neuronavigation system is potentially feasible for feline brain biopsy. The demonstrated accuracy substantiates its clinical utility for feline brain lesions [Formula: see text][Formula: see text]mm, and is comparable to that of other neuronavigation systems described in dogs.
{"title":"ACCURACY OF A FRAMELESS OPTICAL STEREOTACTIC NEURONAVIGATION SYSTEM FOR BRAIN BIOPSY IN CATS: A CADAVERIC STUDY","authors":"Chin-Chieh Yang, Wei-Hsiang Huang, Ya-Pei Chang","doi":"10.1142/s1682648524500021","DOIUrl":"https://doi.org/10.1142/s1682648524500021","url":null,"abstract":"Image-guided stereotactic techniques can display the locations of surgical instruments and biopsy targets in real time, allowing minimally invasive brain biopsies with reduced risk. This study aimed to assess the accuracy of an optical frameless neuronavigation system in feline cadavers and describe potential influencing factors. Phantom lesions were created in different brain regions and depths in 15 feline cadavers. After installing eight fiducial markers in the frontal bone and zygomatic arches, magnetic resonance imaging (MRI) was performed, and the images were imported into the neuronavigation system. Following patient and instrument registration, diluted gadolinium was injected into the phantom lesion (target), guided by the neuronavigation system. The coordinates of the target and contrast points were determined on repeated MRI scans and the distance between them was defined as the targeting error. The time from target selection to the completion of gadolinium injection was recorded as the required time. The targeting error and required time were compared between the initial 30% and final 30% of the collected data to assess the influence of operator experience. Among 76 lesions, the mean targeting error was [Formula: see text][Formula: see text]mm (95% confidence interval 2.76–3.15[Formula: see text]mm). Lesion location, lesion depth, and operator experience did not affect the accuracy; however, operator experience reduced the required time. This frameless optical neuronavigation system is potentially feasible for feline brain biopsy. The demonstrated accuracy substantiates its clinical utility for feline brain lesions [Formula: see text][Formula: see text]mm, and is comparable to that of other neuronavigation systems described in dogs.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139526310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.1142/s1682648523500099
Yen-Pei Tan, Ching-Ho Wang
Infectious bronchitis (IB) is common in poultry and difficult to control. Vaccination is currently considered the best way to prevent IB. The IB virus (IBV) isolated in Taiwan could be clustered into two groups, Taiwan Group I (TW-I or TW1) and Taiwan Group II (TW-II or TW2). An IBV strain 3575/08 was isolated from an IBV-vaccinated chicken farm. Through sequencing analysis, this strain was clustered into TW-I. However, through cross-neutralization test, we found that 3575/08 has a serological correlation with TW-I and TW-II, with relatedness (R) values of 14.20% and 10.24%, respectively. Moreover, its R-value with Massachusetts (H120) is 5.64%. The broad cross-reaction with other serotypes, strain 3575/08 might be a good candidate for vaccine preparation. Therefore, we developed a recombinant adenovirus vector IBV 3575/08 S1 subunit vaccine (rAdS1), which utilizes a recombinant adenovirus expression system to induce humoral protective immunity. This adenovirus vector IBV vaccine may aid in the field control of IB in the future.
{"title":"DEVELOPMENT OF ADENOVIRUS VECTOR INFECTIOUS BRONCHITIS VACCINE IN CHICKENS","authors":"Yen-Pei Tan, Ching-Ho Wang","doi":"10.1142/s1682648523500099","DOIUrl":"https://doi.org/10.1142/s1682648523500099","url":null,"abstract":"Infectious bronchitis (IB) is common in poultry and difficult to control. Vaccination is currently considered the best way to prevent IB. The IB virus (IBV) isolated in Taiwan could be clustered into two groups, Taiwan Group I (TW-I or TW1) and Taiwan Group II (TW-II or TW2). An IBV strain 3575/08 was isolated from an IBV-vaccinated chicken farm. Through sequencing analysis, this strain was clustered into TW-I. However, through cross-neutralization test, we found that 3575/08 has a serological correlation with TW-I and TW-II, with relatedness (R) values of 14.20% and 10.24%, respectively. Moreover, its R-value with Massachusetts (H120) is 5.64%. The broad cross-reaction with other serotypes, strain 3575/08 might be a good candidate for vaccine preparation. Therefore, we developed a recombinant adenovirus vector IBV 3575/08 S1 subunit vaccine (rAdS1), which utilizes a recombinant adenovirus expression system to induce humoral protective immunity. This adenovirus vector IBV vaccine may aid in the field control of IB in the future.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138976878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1142/s1682648523720058
Albert Chun-Chun Chuang, Bing-Cheng Guo, Cheng-Yan Li, Jacky Peng-Wen Chan
A Holstein dairy cow on a farm located in central Taiwan gave birth after 281 days of gestation; however fetal membranes were not expelled until 12[Formula: see text]h post-parturition. Preventive antibiotics of ceftiofur (750[Formula: see text]mg) combined with flunixin (750[Formula: see text]mg) were administered intramuscularly for three consecutive days. On day 11 postpartum, expulsion of partial fetal membranes and reddish-brown vaginal discharge with an offensive odor were reported. Intrauterine lavage using 800[Formula: see text]ml of sterile saline and 500[Formula: see text]ml of 0.2% chlorhexidine solution was performed, followed by intrauterine infusion with 300[Formula: see text]ml of 0.5% povidone iodine. On day 21 postpartum, a vaginal discharge score (VDS) of 3 was graded by Metricheck[Formula: see text] and uterine cytology revealed 76.1% polymorphonuclear neutrophils (PMNs), all of which suggested endometritis. An additional intrauterine infusion of 0.5% povidone iodine was subsequently prescribed, followed by two low doses of PGF[Formula: see text] to control uterine infection. On day 49 postpartum, a VDS of 0 with a proportion of 3.8% PMNs was revealed, indicating available criteria for breeding. Estrus induction and timed artificial insemination were scheduled and pregnancy was confirmed 33 days after artificial insemination. In summary, we have demonstrated a successful two-step treatment for a Holstein having retained fetal membranes (RFMs) combined with puerperal metritis (PM) to have a favorable result of 65 days open.
{"title":"CASE REPORT: A SUCCESSFUL STRATEGY FOR TREATMENT OF RETAINED FETAL MEMBRANES COMBINED WITH PUERPERAL METRITIS IN A DAIRY COW","authors":"Albert Chun-Chun Chuang, Bing-Cheng Guo, Cheng-Yan Li, Jacky Peng-Wen Chan","doi":"10.1142/s1682648523720058","DOIUrl":"https://doi.org/10.1142/s1682648523720058","url":null,"abstract":"A Holstein dairy cow on a farm located in central Taiwan gave birth after 281 days of gestation; however fetal membranes were not expelled until 12[Formula: see text]h post-parturition. Preventive antibiotics of ceftiofur (750[Formula: see text]mg) combined with flunixin (750[Formula: see text]mg) were administered intramuscularly for three consecutive days. On day 11 postpartum, expulsion of partial fetal membranes and reddish-brown vaginal discharge with an offensive odor were reported. Intrauterine lavage using 800[Formula: see text]ml of sterile saline and 500[Formula: see text]ml of 0.2% chlorhexidine solution was performed, followed by intrauterine infusion with 300[Formula: see text]ml of 0.5% povidone iodine. On day 21 postpartum, a vaginal discharge score (VDS) of 3 was graded by Metricheck[Formula: see text] and uterine cytology revealed 76.1% polymorphonuclear neutrophils (PMNs), all of which suggested endometritis. An additional intrauterine infusion of 0.5% povidone iodine was subsequently prescribed, followed by two low doses of PGF[Formula: see text] to control uterine infection. On day 49 postpartum, a VDS of 0 with a proportion of 3.8% PMNs was revealed, indicating available criteria for breeding. Estrus induction and timed artificial insemination were scheduled and pregnancy was confirmed 33 days after artificial insemination. In summary, we have demonstrated a successful two-step treatment for a Holstein having retained fetal membranes (RFMs) combined with puerperal metritis (PM) to have a favorable result of 65 days open.","PeriodicalId":22157,"journal":{"name":"Taiwan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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