A survey of waiting lists for kidney transplantation in northeastern Iran

M. Jangi, H. Tabesh, Mahin Ghorban Sabbagh, Ebrahim Khaleghi Baigi, S. M. Mostafavi, Mahmoud Tara
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Abstract

Introduction: End-stage renal disease (ESRD) continues to be a public health challenge. In ESRD patients, renal replacement therapy is essential. Kidney transplantation is considered as an effective therapeutic procedure for ESRD. On the advice of a qualified nephrologist, ESRD patients are registered on a waiting list, seeking organ transplantation. Objectives: This study aimed to report the status of the waiting list for kidney transplantation in the northeastern Iran region, with data covering the time period until 2017. Patients and Methods: The study was conducted at Montaserie hospital in Mashhad, Iran. We reviewed the clinical records of all ESRD patients referred to the hospital, retrospectively. Patients’ data were completed using a data linkage method and analyzed using SPSS version 23. Results: A total of 1956 patients were studied from the waiting list with a mean age of 44.7 ± 14.4 years (3-80 years). The described etiology reveals that the main causes of ESRD were unknown sources (44.1%), diabetes (18.4%) and hypertension (10.9%). Hemodialysis therapy was conducted for 91.1% of the patients. The maximum registered waiting time was 295 months and the minimum was one month, with an average of 63 months. The proportion of patients waiting for the first, second and third kidney transplantation was 86%, 13.2% and 0.7%, respectively. Conclusion: This study highlights that in the population under study, the number of registered patients on the waiting list followed an increasing pattern, while the age of patients decreased. Unfortunately, in most case studies in Iran, the true etiology of nephrology diseases is still unknown. More effort to define the ESRD causes is necessary. The most likely reason for reported cases with unknown etiology is delays in referral problems.
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伊朗东北部肾移植等待名单的调查
终末期肾病(ESRD)仍然是一个公共卫生挑战。对于终末期肾病患者,肾脏替代治疗是必不可少的。肾移植被认为是治疗终末期肾病的有效方法。在一位合格的肾病专家的建议下,ESRD患者被登记在等待名单上,寻求器官移植。目的:本研究旨在报告伊朗东北部地区肾移植等待名单的状况,数据覆盖时间为2017年。患者和方法:本研究在伊朗马什哈德的Montaserie医院进行。我们回顾了所有转介到医院的ESRD患者的临床记录。患者资料采用数据联动法完成,使用SPSS 23版进行分析。结果:共纳入1956例患者,平均年龄44.7±14.4岁(3 ~ 80岁)。病因学分析显示,病因不明(44.1%)、糖尿病(18.4%)和高血压(10.9%)是ESRD的主要病因。91.1%的患者接受了血液透析治疗。登记轮候时间最长为295个月,最短为1个月,平均为63个月。等待第一次、第二次和第三次肾移植的患者比例分别为86%、13.2%和0.7%。结论:本研究强调,在所研究的人群中,登记在等待名单上的患者数量呈增加趋势,而患者年龄则呈下降趋势。不幸的是,在伊朗的大多数病例研究中,肾脏病的真正病因仍然未知。有必要作出更多努力来确定ESRD的原因。报告的病因不明的病例最可能的原因是转诊问题的延误。
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