Uropathogenic Bacterial Resistance isolated from Oncology Center in Mansoura University

yahya bdreldien, M. Abou-Dobara, A. El-Sayed, Mohamed Zaghloul
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Abstract

Infections of Urinary tract are one of the significant to recommending antibiotic utilization. To involve the most perfect antibiotic for treatment patients, solid and ongoing information about the study of disease transmission and antibiotic resistance of pathogenic bacteria should be accessible for clinicians. So, the normal checking in every nation is required. The points of our review to explore the uropathogenic bacterial variety and antibiotics resistance rates of pathogenic bacteria at the Mansoura Oncology Center (Egypt, Mansoura city) from first October, 2019 to 30th September, 2020 and furthermore to add to checking and topographical variation of treatment by antibiotic. 150 urine samples by aretrospective analysis at Mansoura Oncology Center was processed according to the perfect protocol of urine analysis. Current results were prepared to obtain the prevalence of Urinary tract infections, antibiotics bacterial resistance, time over evolution, and multidrug resistance rate. Bacteria collected from 100 samples were the Escherichia coli and Klebsiella pneumoniae were to be the most identified with 42.0%, and 35.0% respectively. Other main detected species were Enterococci (9%), Pseudomonas (5%), Proteus mirabilis (4%), Citrobacter (2%), Breundimona (1%), Raoultella (1%), and Kluyvera cryocre-scens (1%). Resistance tests to antibiotics indicated K. pneumoniae was more resistance to Cefotriaxon 39.3%, while E. coli was resistant to Ciprofloxacin and Levofloxacin by 41.8%. The variety of some uropathogenic bacteria acquired had all the reserves of being resistant to various antibiotics. Ready faciing by arestorative impasse and the coming of bacteria with multi-resistant, recognizing explicit causes also is significant to adjust antibiotic treatment.
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曼苏拉大学肿瘤中心尿路病原菌耐药性分离株
尿路感染是推荐使用抗生素的重要因素之一。为了让治疗患者使用最完美的抗生素,临床医生应该能够获得有关疾病传播和致病菌抗生素耐药性研究的可靠和持续的信息。因此,每个国家都需要进行正常的检查。目的探讨2019年10月1日至2020年9月30日埃及曼苏拉肿瘤中心尿路病原菌种类及病原菌耐药率,并对抗生素治疗的地形变化进行检查。曼苏拉肿瘤中心回顾性分析尿液样本150份,按照完善的尿液分析方案进行处理。目前的结果是准备获得尿路感染的患病率,抗生素细菌耐药性,进化时间和多药耐药率。其中大肠杆菌和肺炎克雷伯菌的检出率最高,分别为42.0%和35.0%。其他主要检出菌种为肠球菌(9%)、假单胞菌(5%)、奇异变形杆菌(4%)、柠檬酸杆菌(2%)、布隆地莫纳菌(1%)、拉乌尔氏菌(1%)和低温克卢韦拉菌(1%)。抗生素耐药试验结果显示,肺炎克雷伯菌对头孢曲松的耐药率为39.3%,大肠杆菌对环丙沙星和左氧氟沙星的耐药率为41.8%。所获得的部分尿路病原菌品种具有对各种抗生素耐药的全部储备。面对恢复性的僵局和多重耐药细菌的到来,认识明确的原因对调整抗生素治疗也具有重要意义。
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