An effective strategy for the treatment of toxic dyspepsia in calves

Abstract

Relevance. In this paper, an effective protocol for the treatment of a toxic form of dyspepsia in young cattle is considered. According to experts, dyspepsia is a multifactorial disease, the positive outcome of treatment of which depends not only on the effective action of antibacterial therapy, but also on the timely prevention of the development of endotoxic shock, developing due to dehydration and overexpression of the nervous system.The studies were carried out on cattle calves up to 10 days of age of the Holstein breed. To study the therapeutic efficacy of the proposed treatment protocol, three groups of analogues were formed: two experimental and a control group (n=12). The calves of the first experimental group were prescribed: a decoction of oak bark inside, an antibiotic intramuscularly and intraperitoneal preparation "Sterofundin isotonic". In the second experimental group, pathogenetic therapy in the form of visceral novocaine blockade was carried out in addition to the first scheme. In the control group, they were prescribed: inside decoction of oak bark, an antibiotic intramuscularly, the drug "Sterofundin isotonic" intravenously. During the observation period, the general clinical condition was determined daily in the morning and evening. At the end of the experiment, the number of recovered calves, the severity of the disease, and the percentage of animal deaths were determined. On the first day and after 10 days, blood was taken from all animals to determine the dynamics of hematological changes.The use of a treatment regimen for toxic dyspepsia of calves with the inclusion of antibacterial, infusion therapy with simulta neous visceral novocaine blockade allowed to reduce the incidence by 2.7 times, increase therapeutic efficacy by 2.4 times compared with the control group. The duration of treatment with the use of the proposed treatment was reduced by 1.9 days, a significant increase in hemoglobin was noted in the blood of calves by 11.48% higher, lymphocytes by 1.68 times (p<0.05). The economic effect in the second experimental group was maximum and amounted to 2.28 rubles per rub of costs.