Study on Preventive Intervention of Peri-knee Ecchymosis After Total Knee Replacement

Dabiao Hou, Yong-gang Tang, Chun-Hou Huang, Wenrui Wu, Hongyi Zhang, Dong-Lin Luo
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Abstract

Objective: To investigate the effectiveness, controllability and safety of fresh plasma infusion in preventing ecchymosis after total knee arthroplasty (TKA). Methods: Patients with osteoarthritis of the knee who received the initial TKA were assigned to study group, control group, and blank control group according to APTT and PT results on the first day postoperatively. Patients in the study group received 400ml fresh frozen plasma infusion on the first day after TKA, and patients in the control group and blank control group received conventional postoperative treatment. The incidence of ecchymosis, the circumference of the affected limb and visual analog scale (VAS) were compared and analyzed in the three groups. Results: 20 patients were included into each group, respectively. After the infusion of fresh frozen plasma, the number of peri-knee ecchymosis in the study group was significantly less than that in the control group on the 7th and 14th days after the operation (P 0.05). On the 7th and 14th day after surgery, the pain degree of the three groups was relieved, and the VAS score of the study group and the blank control group showed no statistically significant difference (P>0.05), while the VAS score of the study group was lower than that of the control group, the difference was statistically significant (P<0.05). Conclusion: For patients with abnormal coagulation function after TKA, timely postoperative infusion of fresh frozen plasma can reduce the incidence of postoperative ecchymosis and relieve pain, which has certain clinical reference significance.
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全膝关节置换术后膝关节周围瘀斑的预防干预研究
目的:探讨新鲜血浆输注预防全膝关节置换术后瘀斑的有效性、可控性和安全性。方法:根据术后第1天APTT和PT结果,将首次行TKA的膝关节骨性关节炎患者分为研究组、对照组和空白对照组。研究组患者在TKA术后第一天给予400ml新鲜冷冻血浆输注,对照组和空白对照组患者给予术后常规治疗。比较分析三组患者瘀斑发生率、患肢围度及视觉模拟评分(VAS)。结果:每组各纳入20例患者。术后第7、14天,输注新鲜冷冻血浆后,研究组患者膝周瘀斑数量明显少于对照组(P < 0.05)。术后第7、14天,三组患者疼痛程度均有所缓解,研究组与空白对照组VAS评分差异无统计学意义(P>0.05),而研究组VAS评分低于对照组,差异有统计学意义(P<0.05)。结论:对于TKA术后凝血功能异常的患者,术后及时输注新鲜冷冻血浆可降低术后瘀斑的发生率,减轻疼痛,具有一定的临床参考意义。
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