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A Case Report of Mesenteric Ischemia After COVID-19 Vaccination COVID-19疫苗接种后肠系膜缺血1例报告
Pub Date : 2021-08-31 DOI: 10.11648/J.JS.20210904.23
S. Gaudio, F. E. Gaudio
The United States has vaccinated almost 200 million citizens in the first 7 months of 2021. During that period adverse events have been described from minor complaints of redness, pain and swelling at the injection site to more serious events such as Guillain Barre Syndrome and thrombosis. As vaccination distribution continue to move forward, more side effects and complications will become evident. This case report is of a patient presenting in shock 4 days after receiving her second COVID-19 vaccination with altered mental status, dyspnea, and an acute abdomen with a bowel perforation. After resuscitation, the patient was taken to surgery where an additional diagnosis of embolic mesenteric arterial ischemia was made on exploratory laparotomy. While a causal relationship between the vaccine and the findings in this particular patient cannot be proven, there certainly is a temporal relationship between her receiving the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine, the presentation of this patient to our institution, and the findings during emergency surgery. Thromboses are known adverse events from the COVID-19 vaccines however to our knowledge, there has not been a published case report of embolic mesenteric arterial ischemia after receiving a COVID-19 vaccine. Appreciating the association between COVID-19 vaccines and embolic mesenteric arterial ischemia should alert physicians to keep this diagnosis high on their differential in the setting of unusual abdominal pain and recent vaccination.
美国在2021年前7个月为近2亿公民接种了疫苗。在此期间,不良事件的描述从轻微的红肿、疼痛和注射部位肿胀到更严重的事件,如格林-巴利综合征和血栓形成。随着疫苗接种的继续推进,更多的副作用和并发症将变得明显。本病例报告是一名患者在第二次接种COVID-19疫苗4天后出现休克,伴有精神状态改变、呼吸困难和急腹症并肠穿孔。复苏后,患者被送往手术,并在剖腹探查时进一步诊断为栓塞性肠系膜动脉缺血。虽然疫苗与该特定患者的结果之间的因果关系无法证明,但她接受辉瑞- biontech (BNT162b2) COVID-19疫苗,该患者到我们机构就诊以及急诊手术期间的结果之间肯定存在时间关系。血栓形成是已知的COVID-19疫苗不良事件,但据我们所知,尚未发表过接种COVID-19疫苗后栓塞性肠系膜动脉缺血的病例报告。认识到COVID-19疫苗与栓塞性肠系膜动脉缺血之间的关联,应提醒医生在异常腹痛和最近接种疫苗的情况下保持这种诊断的高度鉴别。
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引用次数: 0
The Intraoperative Finding of a Large Atrial Septum Defect Pre-Liver Transplantation: A Case Report 肝移植前术中发现大面积房间隔缺损1例
Pub Date : 2021-08-27 DOI: 10.11648/J.JS.20210904.21
A. Rebel, L. Hampton, Zaki-Udin Hassan, M. Shah
The case report discusses a significant discrepancy between the pre-transplant cardiac evaluation and post-induction transesophageal echocardiography, leading to aborting the surgical procedure. The transthoracic echocardiography [TTE] pre-liver transplant indicated only a minor intracardiac shunt, while the post-induction transesophageal echocardiography [TEE] showed a large atrial septal defect with a more significant left to right shunt. The attempt to close the defect with a transcatheter closure device failed and the perioperative care team decided not to proceed with the liver transplantation. Later cardiac evaluation with cardiac magnetic resonance imaging demonstrated a secundum atrial septum defect in the inferior border of the interatrial septum with 43 ml flow difference between systemic and pulmonary circulation. The failure to identify a large atrial septal defect/inferior venosus defect in the preoperative screening process for liver transplantation resulted in failing to optimize the patient pre transplant. Although complications related to large atrial septal defects are rare during liver transplant (paradoxical embolisms, malignant arrhythmias, myocardial infarctions or cerebrovascular complications), they can be potentially fatal. The preoperative cardiac assessment should have included optimization of this congenital defect. The case report discusses implications of atrial septal defects for liver transplant and why the screening process may have missed the defect. The findings of a positive bubble study during the transthoracic echocardiography should not be trivialized and may require further workup.
病例报告讨论了移植前心脏评估与诱导后经食管超声心动图之间的显著差异,导致手术流产。肝移植前经胸超声心动图[TTE]显示只有轻微的心内分流,而诱导后经食管超声心动图[TEE]显示有较大的房间隔缺损,左向右分流更为明显。尝试用经导管闭合装置闭合缺陷失败,围手术期护理小组决定不进行肝移植。后来的心脏磁共振成像检查显示心房间隔下缘有二次房间隔缺损,体循环和肺循环血流差43 ml。在肝移植术前筛查过程中未能发现较大的房间隔缺损/下静脉缺损,导致患者移植前未能优化。虽然在肝移植过程中与大房间隔缺损相关的并发症(矛盾栓塞、恶性心律失常、心肌梗死或脑血管并发症)很少见,但它们可能是致命的。术前心脏评估应包括先天性缺陷的优化。本病例报告讨论了房间隔缺损对肝移植的影响,以及为什么筛查过程可能会遗漏房间隔缺损。在经胸超声心动图中发现的阳性气泡不应被轻视,可能需要进一步的检查。
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引用次数: 0
Short Term Outcomes of Laparoscopic Roux-En-Y Gastric Bypass Versus Laparoscopic One Anastomosis Gastric Bypass in Super Obese Patients: Randomized Clinical Trial 腹腔镜Roux-En-Y胃旁路术与腹腔镜一次吻合胃旁路术治疗超肥胖患者的短期疗效:随机临床试验
Pub Date : 2021-08-27 DOI: 10.11648/J.JS.20210904.22
Mahmoud El Ghoneimy Abd El-Sadek, A. Swelam, H. Abd-Allah, G. Moussa, Osama Helmy El Khadrawy
Background: One anastomosis gastric bypass (OAGB) has several apparent advantages over Roux-En-Y Gastric Bypass (RYGB). However, symptomatic biliary reflux and its potential risks have prevented its widespread adoption. The aim of this study was to assess the short term outcomes of LOAGB in comparison to LRYGB in treatment of patients with super obesity regarding weight loss, resolution/improvement of co-morbidities and impact on patients’ quality of life (QoL). Methods: One hundred adult patients with super obesity were randomly divided into 2 matched groups, 50 patients each; group I underwent LRYGB and group II underwent LOAGB. Results: The operative time was significantly longer in LRYGB (176.4±27.29 vs. 110.5±14.13 minutes, p<0.05). The frequency and severity of the early postoperative complications were comparable between both groups. No mortality or re-admission was reported in both groups. There are no patients lost to follow-up. Although, the mean Excess weight loss percent (EWL%) was 57% vs 64.7% and 69.7% vs 75.5% at one and two years follow-up in group I and II respectively, the differences were statistically insignificant. T2DM remission/improvement rates at 12th month were 88.9% and 94.1% in group I and II respectively without a statistically insignificant difference. In comparison to the preoperative Qol score, the postoperative score showed a statistically significant improvement (from 0.31 to 6 and from 0.41 to 6.32 in group I and II respectively). Conclusions: LOAGB had a shorter operative time and a tendency towards a higher EWL%, a better remission of obesity-related comorbidities and improvement in the patients QoL with comparable short term operative and postoperative complications. Thus, LOAGB can be considered an acceptable alternative to LRYGB in management of super obese patients.
背景:一次吻合胃旁路术(OAGB)与Roux-En-Y胃旁路术(RYGB)相比有几个明显的优势。然而,症状性胆汁反流及其潜在风险阻碍了其广泛采用。本研究的目的是评估LOAGB与LRYGB在治疗超级肥胖患者方面的短期结果,包括体重减轻、合并症的解决/改善以及对患者生活质量(QoL)的影响。方法:100例成人超肥胖患者随机分为2组,每组50例;ⅰ组行LRYGB,ⅱ组行LOAGB。结果:LRYGB组手术时间(176.4±27.29分钟)明显长于LRYGB组(110.5±14.13分钟),p<0.05。两组术后早期并发症的发生频率和严重程度具有可比性。两组均无死亡或再入院报告。没有患者因随访而丢失。虽然在1年和2年的随访中,I组和II组的平均超重减重率(EWL%)分别为57%对64.7%和69.7%对75.5%,但差异无统计学意义。I组和II组12个月T2DM缓解/改善率分别为88.9%和94.1%,差异无统计学意义。与术前生活质量评分相比,术后生活质量评分有统计学意义的提高(I组从0.31提高到6,II组从0.41提高到6.32)。结论:LOAGB具有较短的手术时间和较高的EWL%的趋势,较好地缓解了肥胖相关的合并症,改善了患者的生活质量,且短期手术和术后并发症相当。因此,LOAGB可以被认为是治疗超级肥胖患者的一种可接受的替代方案。
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引用次数: 0
Study on Preventive Intervention of Peri-knee Ecchymosis After Total Knee Replacement 全膝关节置换术后膝关节周围瘀斑的预防干预研究
Pub Date : 2021-08-09 DOI: 10.11648/J.JS.20210904.20
Dabiao Hou, Yong-gang Tang, Chun-Hou Huang, Wenrui Wu, Hongyi Zhang, Dong-Lin Luo
Objective: To investigate the effectiveness, controllability and safety of fresh plasma infusion in preventing ecchymosis after total knee arthroplasty (TKA). Methods: Patients with osteoarthritis of the knee who received the initial TKA were assigned to study group, control group, and blank control group according to APTT and PT results on the first day postoperatively. Patients in the study group received 400ml fresh frozen plasma infusion on the first day after TKA, and patients in the control group and blank control group received conventional postoperative treatment. The incidence of ecchymosis, the circumference of the affected limb and visual analog scale (VAS) were compared and analyzed in the three groups. Results: 20 patients were included into each group, respectively. After the infusion of fresh frozen plasma, the number of peri-knee ecchymosis in the study group was significantly less than that in the control group on the 7th and 14th days after the operation (P 0.05). On the 7th and 14th day after surgery, the pain degree of the three groups was relieved, and the VAS score of the study group and the blank control group showed no statistically significant difference (P>0.05), while the VAS score of the study group was lower than that of the control group, the difference was statistically significant (P<0.05). Conclusion: For patients with abnormal coagulation function after TKA, timely postoperative infusion of fresh frozen plasma can reduce the incidence of postoperative ecchymosis and relieve pain, which has certain clinical reference significance.
目的:探讨新鲜血浆输注预防全膝关节置换术后瘀斑的有效性、可控性和安全性。方法:根据术后第1天APTT和PT结果,将首次行TKA的膝关节骨性关节炎患者分为研究组、对照组和空白对照组。研究组患者在TKA术后第一天给予400ml新鲜冷冻血浆输注,对照组和空白对照组患者给予术后常规治疗。比较分析三组患者瘀斑发生率、患肢围度及视觉模拟评分(VAS)。结果:每组各纳入20例患者。术后第7、14天,输注新鲜冷冻血浆后,研究组患者膝周瘀斑数量明显少于对照组(P < 0.05)。术后第7、14天,三组患者疼痛程度均有所缓解,研究组与空白对照组VAS评分差异无统计学意义(P>0.05),而研究组VAS评分低于对照组,差异有统计学意义(P<0.05)。结论:对于TKA术后凝血功能异常的患者,术后及时输注新鲜冷冻血浆可降低术后瘀斑的发生率,减轻疼痛,具有一定的临床参考意义。
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引用次数: 0
Late Primary B Cell Cerebral Lymphoma After Kidney Transplant: A Case Report and Literature Review 肾移植后晚期原发性脑B细胞淋巴瘤1例报告及文献复习
Pub Date : 2021-08-02 DOI: 10.11648/J.JS.20210904.19
Isabella Opoku, Linghao Tang, Lidan Jiang, Dan Wang, Xu Yueqiao, Lin Feng, Wang Ning
Background: Primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD) is a serious and uncommon complication which can be developed months or years after a Kidney transplant. Immunosuppressive agents administered before and after transplantation to minimize the chances of allograft rejection has proved to be a double-edged sword that puts the host at risk of infectious, neoplastic and vascular diseases, including PCNS-PTLD. The immunosuppressive therapy leads to decreased innate malignant and viral immune surveillance and this has been shown to play a role in lymphoproliferative diseases after transplantation. In most cases, PCNS-PTLD is Epstein–Barr virus related. Case Description: A 60-year-old female with history of kidney transplant presented to the emergency room with history of low fever, dizziness nausea and vomiting for 1 month. MRI and CT scans showed a mass cerebellar lesion and a biopsy revealed Primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD). Conclusion: This case highlights the need for a careful long-term follow up of patients with kidney transplant. PCNS-PTLD represents a continuing long-term risk after transplantation, although less common. This case report supports observational data that suggests that peripheral blood screening for EBV DNA does not seem helpful for identification of PCNS-PTLD. Suspicion of PCNS PTLD should be considered when patients with long-term history of kidney transplant present neurological complaints.
背景:原发性中枢神经系统移植后淋巴细胞增生性疾病(PCNS-PTLD)是一种严重而罕见的并发症,可在肾移植后数月或数年发生。在移植前后使用免疫抑制剂以减少同种异体移植排斥的机会已被证明是一把双刃剑,它使宿主面临感染性、肿瘤性和血管疾病的风险,包括PCNS-PTLD。免疫抑制治疗导致先天恶性和病毒免疫监视下降,这已被证明在移植后淋巴增生性疾病中发挥作用。在大多数情况下,pns - ptld与爱泼斯坦-巴尔病毒有关。病例描述:60岁女性,有肾移植史,以低烧、头晕恶心呕吐1个月就诊于急诊室。MRI和CT扫描显示肿块小脑病变,活检显示原发性中枢神经系统移植后淋巴细胞增生性疾病(PCNS-PTLD)。结论:本病例强调了对肾移植患者进行长期随访的必要性。PCNS-PTLD在移植后持续存在长期风险,尽管不太常见。该病例报告支持观察数据,表明外周血EBV DNA筛查似乎无助于PCNS-PTLD的鉴定。当有长期肾移植史的患者出现神经系统疾患时,应考虑PCNS PTLD的怀疑。
{"title":"Late Primary B Cell Cerebral Lymphoma After Kidney Transplant: A Case Report and Literature Review","authors":"Isabella Opoku, Linghao Tang, Lidan Jiang, Dan Wang, Xu Yueqiao, Lin Feng, Wang Ning","doi":"10.11648/J.JS.20210904.19","DOIUrl":"https://doi.org/10.11648/J.JS.20210904.19","url":null,"abstract":"Background: Primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD) is a serious and uncommon complication which can be developed months or years after a Kidney transplant. Immunosuppressive agents administered before and after transplantation to minimize the chances of allograft rejection has proved to be a double-edged sword that puts the host at risk of infectious, neoplastic and vascular diseases, including PCNS-PTLD. The immunosuppressive therapy leads to decreased innate malignant and viral immune surveillance and this has been shown to play a role in lymphoproliferative diseases after transplantation. In most cases, PCNS-PTLD is Epstein–Barr virus related. Case Description: A 60-year-old female with history of kidney transplant presented to the emergency room with history of low fever, dizziness nausea and vomiting for 1 month. MRI and CT scans showed a mass cerebellar lesion and a biopsy revealed Primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD). Conclusion: This case highlights the need for a careful long-term follow up of patients with kidney transplant. PCNS-PTLD represents a continuing long-term risk after transplantation, although less common. This case report supports observational data that suggests that peripheral blood screening for EBV DNA does not seem helpful for identification of PCNS-PTLD. Suspicion of PCNS PTLD should be considered when patients with long-term history of kidney transplant present neurological complaints.","PeriodicalId":101237,"journal":{"name":"The Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86339173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balloon Dilatation of the Pylorus After Gastric Pull-up in a Single Centre 单中心胃上拉后幽门球囊扩张
Pub Date : 2021-07-29 DOI: 10.11648/J.JS.20210904.17
Alexander Bech Rasmussen, B. N. Jepsen, F. hvid-Jensen, N. Katballe, D. Kjaer
Background: The mainstay of intended curative treatment for esophagus cancer is surgery. Symptoms of gastric outlet obstruction can occur in some patients postoperatively. Some of these patients require alleviating treatment which may include balloon dilatation of the pylorus. The aim of this study was to investigate the use for balloon dilatation of the pylorus following esophagectomy in patients treated for carcinoma of the esophagus with intent to cure. Methods: A retrospective study of 120 patients who underwent esophagectomy with gastric pull-up at Aarhus University Hospital, Denmark, between January 2017 and December 2018 and were followed until December 2020. Primary outcome was number of postoperative balloon dilatations of the pylorus. Results: A total of 63 patients (53%) went through at least 1 balloon dilatation of the pylorus, 40 (63%) needed more than 1 dilatation. The median time between esophagectomy and first dilatation was two months. There was a strong association between squamous cell carcinoma and postoperative dilatation compared to adenocarcinoma (OR=4.13). An association was also seen between ex-smokers and postoperative dilatation compared to non-smokers (OR=3.95). Conclusions: More than fifty percent of the patients needed postoperative balloon dilatation. The need for dilatations was strongest between the second and the ninth postoperative month. A nationwide multicentre study of gastric pull-up patients is needed in the future to develop clinical tools to assess the need for pyloric dilatation.
背景:食管癌的主要治疗方法是手术。部分患者术后可出现胃出口梗阻症状。其中一些患者需要减轻治疗,其中可能包括幽门球囊扩张。本研究的目的是探讨食管癌术后幽门球囊扩张术在治疗目的为治愈食管癌患者中的应用。方法:对2017年1月至2018年12月在丹麦奥胡斯大学医院接受食管切除术合并胃上拉治疗的120例患者进行回顾性研究,随访至2020年12月。主要观察指标为术后幽门球囊扩张次数。结果:63例(53%)患者行幽门球囊扩张1次以上,40例(63%)患者行幽门球囊扩张1次以上。从食管切除术到第一次扩张的中位时间为2个月。与腺癌相比,鳞状细胞癌与术后扩张有很强的相关性(OR=4.13)。与非吸烟者相比,戒烟者与术后扩张之间也存在关联(OR=3.95)。结论:超过50%的患者术后需要球囊扩张。术后第2个月至第9个月对扩张的需求最强。未来需要对胃引体抬高患者进行全国性的多中心研究,以开发临床工具来评估幽门扩张的必要性。
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引用次数: 0
Bifocal Patellar Tendon Avulsion Fracture in a Child 儿童双焦点髌骨肌腱撕脱性骨折
Pub Date : 2021-07-29 DOI: 10.11648/J.JS.20210904.18
Elisa Mareddu, J. Corbaz, R. Desmarchelier, A. Traverso
The avulsion fracture of the patellar tendon from its proximal and distal attachment is extremely rare. Only a few cases have been described in the English literature and many aspects are still poorly understood. During our practice we came across the case of a 13 year old boy with the above mentioned lesion that we present hereby. Other than describing our experience we tried to tackle the different questions surrounding this lesion, with a careful analysis of the previous reports. A “weaker bone” was considered the main risk factor without any connection with a particular disease or condition. We found out that it is a mainly a pediatric problem, due to the particular bone structure of this population, with many of the subjects being affected by Osgood–Schlatter disease. Different authors have reported their experiences and hypothesis concerning the mechanism behind this injury that has yet to be clearly defined. However most of them mentioned an eccentric load over a knee in forced flexion, leading us to believe that this could be the main source of this unique type of disruption of the extensor apparatus of the knee. Moreover the diagnosis can be quite challenging with many authors advocating for the use of advanced imaging. Treatment options are multiples and the choice relies for the most part on the practitioner preference. From what emerged from the available data it is almost exclusively surgical. Independently from the selected technique, the outcomes are generally favorable.
髌骨肌腱近端和远端附着处撕脱骨折极为罕见。只有少数案例在英语文献中被描述,许多方面仍然知之甚少。在我们的实践中,我们遇到的情况下,一个13岁的男孩与上述病变,我们在此提出。除了描述我们的经验外,我们还试图通过对先前报告的仔细分析来解决围绕这一病变的不同问题。“骨骼较弱”被认为是主要的危险因素,与特定疾病或状况没有任何关系。我们发现这主要是一个儿科问题,由于这一人群的特殊骨骼结构,许多受试者都受到奥斯古德-施莱特病的影响。不同的作者报告了他们的经验和关于这种损伤背后的机制的假设,但尚未明确定义。然而,他们中的大多数都提到了强迫屈曲时膝盖上的偏心负荷,这使我们相信这可能是这种独特类型的膝关节伸肌破坏的主要原因。此外,由于许多作者提倡使用先进的成像技术,诊断可能相当具有挑战性。治疗方案是多种多样的,选择在很大程度上取决于医生的偏好。从现有数据来看,这几乎完全是外科手术。与所选择的技术无关,结果通常是有利的。
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引用次数: 0
CSF Leak Post COVID-19 Swab in a Patient with Preexisting Meningiocele 既往脑膜膨出患者COVID-19拭子后脑脊液泄漏
Pub Date : 2021-06-28 DOI: 10.11648/J.JS.20210904.16
Alzuwayed Abdullah, Algouhi Amani, Alshafi Mohammad, Alhedaithy Riyadh
A 45-year-old female with medical background significant for bronchial asthma, hypothyroidism, polycystic kidney disease and obesity presented to the emergency department in December 2020 with one week history of severe headache, unilateral rhinorrhea and metallic taste. Her symptoms started two days after she had nasopharyngeal swab as post travel screening routine. Radiological investigations revealed features of increased intracranial pressure and a suspicious skull base defect for which patient undergone endoscopic transnasal skull base repair. Intraoperative findings were positive for CSF leak from a skull base defect and an incidental finding of Meningiocle. Patient was seen after three weeks with no more CSF rhinorrhea, but was complaining of persistent mild headache, for which she was referred to neurology for further management. Conclusion: CSF leak is one of the rare, yet serious complications of nasopharyngeal swab especially in patients with previous skull base surgery, trauma, patients with pre-existing skull base defects or with elevated intracranial pressure. Meningocele found in this case report was presumed to be a predisposing factor for CSF leak post nasopharyngeal swab. Education about safe administration of nasopharyngeal swabs as well as understanding the nose anatomy is important to reduce the overall risk profile of nasopharyngeal sampling. Moreover, an alternative method of testing such as oropharyngeal specimen should be considered in populations with increased risk of CSF leak.
45岁女性,医学背景为支气管哮喘、甲状腺功能减退、多囊肾病和肥胖,于2020年12月就诊急诊科,伴有严重头痛、单侧鼻漏和金属味一周。她的症状是在作为旅行后筛查常规使用鼻咽拭子两天后出现的。影像学检查显示颅内压升高和可疑颅底缺损,患者接受经鼻内镜颅底修复。术中发现脑脊液漏来自颅底缺损和偶然发现脑膜膜。患者就诊三周后不再有脑脊液鼻漏,但主诉持续轻度头痛,因此转至神经内科进一步治疗。结论:脑脊液漏是鼻咽拭子术后罕见但严重的并发症之一,尤其适用于颅底手术、外伤、颅底缺损及颅内压增高患者。在本病例报告中发现的脑膜膨出被认为是鼻咽拭子后脑脊液泄漏的易感因素。关于鼻咽拭子安全使用的教育以及对鼻解剖的了解对于降低鼻咽取样的总体风险非常重要。此外,在脑脊液泄漏风险增加的人群中,应考虑另一种检测方法,如口咽标本。
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引用次数: 1
A Case of Rectal Carcinoma Complicated with Adult T-cell Leukemia/Lymphoma Diagnosed by an Inguinal Lymph Node Biopsy 腹股沟淋巴结活检诊断直肠癌合并成人t细胞白血病/淋巴瘤1例
Pub Date : 2021-06-23 DOI: 10.11648/J.JS.20210904.14
M. Kuwahara, T. Goto, Shintaro Yamamoto, Takanobu Sugase, N. Inadome, H. Hojo, K. Ibusuki, S. Taniguchi, H. Kawano, Hiroshi Tai, Keiko Umekita, Hiroyuki Tanaka, Rintaro Koga
Background: Recently, double cancer is no longer uncommon. It is Particularly difficult to determine whether swollen lymph nodes (LNs) indicate malignant lymphoma or metastasis of other carcinoma. We experienced a case of rectal carcinoma complicated with adult T-cell leukemia/lymphoma (ATLL). Case presentation: We encountered a 77-year-old woman who had visited a previous hospital due to bloody stool. Colonoscopy revealed a 10-cm tumor in the lower rectum. Given its pit pattern and surface and vessel pattern, she was suspected of having adenocarcinoma in situ. However, enhanced computed tomography (CT) showed LN swelling around the rectum, and her bilateral inguinal LNs were palpable. Colonoscopy and a biopsy performed at our hospital showed adenoma (Group 3) with no malignant findings. We performed an inguinal LN biopsy and diagnosed her with ATLL. We suspected the rectal mass either be rectal carcinoma or ATLL invasion. We performed chemotherapy for ATLL. The inguinal LNs became no longer palpable, but the rectal mass did not shrink, so we performed operative resection for diagnostic treatment. Thereafter, we diagnosed her with double cancer of rectal adenocarcinoma and ATLL. Conclusion: It is difficult to determine whether swollen LNs indicate malignant lymphoma or metastasis of other carcinoma without performing an LN biopsy. However, a diagnosis of metastasis or non-metastasis does not influence either the staging of the carcinoma or the treatment plan.
背景:近年来,双癌已不再罕见。尤其难以确定淋巴结肿大是否为恶性淋巴瘤或其他癌的转移。我们报告一例直肠癌合并成人t细胞白血病/淋巴瘤(ATLL)。病例介绍:我们遇到一位77岁的妇女,她曾因便血去医院就诊。结肠镜检查显示直肠下部有一个10厘米的肿瘤。鉴于其凹状形态、表面及血管形态,怀疑为原位腺癌。然而,增强CT显示直肠周围淋巴结肿大,双侧腹股沟淋巴结可触及。结肠镜检查和活检显示腺瘤(第3组),无恶性发现。我们对她进行了腹股沟淋巴结活检并诊断为ATLL。我们怀疑直肠肿块可能是直肠癌或ATLL侵袭。我们对ATLL进行了化疗。腹股沟LNs不再可触及,但直肠肿块没有缩小,因此我们行手术切除进行诊断治疗。此后,我们诊断她为直肠腺癌和ATLL双重癌。结论:如果不进行淋巴结活检,很难确定肿胀的淋巴结是恶性淋巴瘤还是其他癌的转移。然而,转移或非转移的诊断并不影响癌症的分期或治疗计划。
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引用次数: 0
Autologous Reconstruction Following Nipple Sparing Mastectomy Achieves Equivalent Aesthetic Outcome as Natural Breasts 保留乳头乳房切除术后自体乳房重建达到与自然乳房相同的美学效果
Pub Date : 2021-06-22 DOI: 10.11648/J.JS.20210904.15
Peter L. Deptula, Youna K. Choi, Nhung Tran, D. Rochlin, D. Nguyen
We determined the aesthetic outcomes of autologous breast reconstruction in comparison to cosmetically altered or natural breasts. We also examined the effect of perceptions on aesthetic outcomes of breast reconstruction. Images of 10 patients (autologous breast reconstruction following bilateral nipple sparing mastectomy (NSM) (n=5), bilateral breast reduction (n=1), bilateral mastopexy (n=1), bilateral augmentation (n=1), unoperated natural breasts (n=2)), were compiled into a blind three-part survey. Part one asked participants to determine whether the presented breasts are reconstructed after mastectomy and measure aesthetic outcomes (1=poor and 4=excellent). Part two ranks breasts from most desirable to least desirable. Part three presents side-by-side unlabeled pre and postoperative images of patients who have undergone autologous breast reconstruction and asks to select the more aesthetically pleasing breasts. Two thousand images were quantified from 100 surveys (83.3% response rate). Age range of participants was 18-80. Response was not statistically different based on demographics. The rate of correctly identifying breasts as reconstruction after NSM was 62.8% and as natural was 64%. Mean aesthetic scores between the reconstructed and natural breasts were equivalent. Breasts perceived as reconstruction scored significantly lower in five aesthetic factors. The top 3 most desired breasts were augmentation, reconstruction after NSM, and unoperated natural breasts. In paired pre- and postoperative photo comparison, all responses favored postoperative breasts. Aesthetic outcomes after autologous breast reconstruction can be equivalent to natural breasts. Breasts perceived as reconstruction are ranked poorer in aesthetic factors compared to those perceived as natural breasts.
我们确定了自体乳房重建的美学结果与美容改变或自然乳房的比较。我们还研究了感知对乳房重建美学结果的影响。10例患者(双侧乳头保留乳房切除术(NSM)后自体乳房重建(n=5),双侧乳房缩小(n=1),双侧乳房切除术(n=1),双侧乳房隆胸(n=1),未手术的自然乳房(n=2))的图像被收集成一个盲法三部分调查。第一部分要求参与者确定乳房切除后所呈现的乳房是否重建,并测量美学结果(1=差,4=好)。第二部分将乳房从最性感到最不性感排列。第三部分展示了接受自体乳房重建的患者的并排未标记的术前和术后图像,并要求选择更美观的乳房。从100份调查中量化了2000张图像(有效率为83.3%)。参与者年龄在18-80岁之间。根据人口统计数据,反应没有统计学差异。NSM术后乳房重建的正确率为62.8%,自然乳房的正确率为64%。重建乳房和天然乳房的平均美学评分相当。乳房再造在五个美学因素上得分明显较低。最受欢迎的前3位乳房分别是隆胸、NSM后再造和未手术的自然乳房。在配对的术前和术后照片比较中,所有的反应都倾向于术后乳房。自体乳房重建后的美观效果可与天然乳房相当。与自然乳房相比,被认为是重建乳房的乳房在美学因素上排名较差。
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The Journal of Surgery
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