{"title":"Assessment of the Mutagenicity of Lycopene by the Ames Test.","authors":"K. Aizawa, T. Inakuma, S. Oshima","doi":"10.1271/NOGEIKAGAKU1924.74.679","DOIUrl":null,"url":null,"abstract":"Lycopene is a hydrocarbon carotenoid in tomato products. We examined the mutagenicity of lycopene by the Ames test, to evaluate the safety of lycopene. Lycopene extracted from tomato paste was added as a solution or suspension in DMSO at 0.05-5000μg per plate. Lycopene showed no detectable mutagenicity on Salmonella typhimurium TA98, TA100, TA1535 and TA1537, and Escherichia coli WP2uvrA- with or without S-9 mix.","PeriodicalId":9443,"journal":{"name":"Bulletin of the Agricultural Chemical Society of Japan","volume":"12 1","pages":"679-681"},"PeriodicalIF":0.0000,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Agricultural Chemical Society of Japan","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1271/NOGEIKAGAKU1924.74.679","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
Lycopene is a hydrocarbon carotenoid in tomato products. We examined the mutagenicity of lycopene by the Ames test, to evaluate the safety of lycopene. Lycopene extracted from tomato paste was added as a solution or suspension in DMSO at 0.05-5000μg per plate. Lycopene showed no detectable mutagenicity on Salmonella typhimurium TA98, TA100, TA1535 and TA1537, and Escherichia coli WP2uvrA- with or without S-9 mix.
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