Demographic, clinical, and serological features of Iraqi patients with rheumatoid arthritis: evaluation of 470 patients

A. Mathkhor, Abdulnasser H. Abdullah Amer S. Khoudhairy
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引用次数: 2

Abstract

Aim: To evaluate the demographic, clinical, serological, and radiological characteristics of patients with Rheumatoid Arthritis (RA). Methods: This was a cross-sectional, descriptive study conducted on a population of patients with RA in the rheumatology outpatient clinic in the three main teaching hospitals in Basrah province between January 2018 and July 2020. Four hundred seventy patients with RA were recruited for this study. All patients were examined and diagnosed by a rheumatologist. Laboratory and radiology tests were also performed for all patients. Results: Three hundred eighty-five (81.9%) women and 85 (18.1%) men with RA were enrolled for the study. The mean age, disease duration, and body mass index were 49.9 ± 11.9, 14.7 ± 6.8 years, and 27.1 ± 4.7, respectively. 322(68.5%) of the patients were have insidious disease onsets. There were 425 (96.2%) patients on Methotrexate (MTX), 247(52.6%), and 180(38.3%) patients on etanercept and prednisolone, respectively. The wrist was the most frequently involved joint, and the hip was the least frequently affected joint (100% and 5.1%), respectively. Anemia was the most extra-articular manifestation in our sample in a ratio of 18.7%. Anti-CCP and rheumatoid factor were present in 81.9% and 77%, respectively. Ulnar deviation was complicated 19.4% of the patients. Diabetes mellitus was the most abundant comorbidity presented in 43.6% of patients. One hundred sixty (34.0%) of the patients were completed their secondary education. Conclusion: Clinical and serological features of rheumatoid arthritis in Basrah province were similar to those found in some national and international studies. We observed higher female preponderance.
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伊拉克类风湿关节炎患者的人口学、临床和血清学特征:对470例患者的评估
目的:评价类风湿关节炎(RA)患者的人口学、临床、血清学和放射学特征。方法:这是一项横断面描述性研究,对2018年1月至2020年7月在巴士拉省三家主要教学医院风湿病门诊就诊的RA患者进行了研究。这项研究招募了470名RA患者。所有患者均由风湿病学家进行检查和诊断。还对所有患者进行了实验室和放射学检查。结果:385名(81.9%)女性和85名(18.1%)男性RA患者入组研究。平均年龄49.9±11.9岁,病程14.7±6.8岁,体重指数27.1±4.7岁。隐匿性发病322例(68.5%)。甲氨蝶呤组425例(96.2%),依那西普组247例(52.6%),强的松龙组180例(38.3%)。腕部是最常受累的关节,髋关节是最不常受累的关节(分别为100%和5.1%)。在我们的样本中,贫血是最常见的关节外表现,比例为18.7%。抗ccp和类风湿因子分别占81.9%和77%。尺侧偏差发生率为19.4%。糖尿病是最常见的合并症,占43.6%。160例(34.0%)患者完成中等教育。结论:巴士拉省类风湿关节炎的临床和血清学特征与一些国内和国际研究结果相似。我们观察到较高的女性优势。
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