MR imaging of Fe-Co nanoparticles, magnetotactic bacteria and Fe3O4 microparticles for future drug delivery applications

O. Felfoul, P. Pouponneau, J. Mathieu, S. Martel
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引用次数: 2

Abstract

Magnetic resonance imaging characteristics of novel potential drug delivery agents are investigated. Candidate carriers considered in this study are iron-cobalt (Fe-Co) nanoparticles, magnetotactic bacteria (MTB), and magnetite (Fe3O4) microparticles. The micro and nanoparticles are highly magnetic and can be steered using gradient coils. MTB, on the other hand, are microorganisms that naturally follow the magnetic field lines through a mechanism called magnetotaxis. These carriers share the capability to be controlled by magnetic field and to be detected on MR images.
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Fe-Co纳米颗粒,趋磁细菌和Fe3O4微颗粒的磁共振成像,用于未来的药物输送应用
研究了新型潜在药物递送剂的磁共振成像特性。本研究考虑的候选载体有铁钴(Fe-Co)纳米颗粒、趋磁细菌(MTB)和磁铁矿(Fe3O4)微粒。微粒子和纳米粒子具有很强的磁性,可以使用梯度线圈来控制。另一方面,结核分枝杆菌是一种微生物,通过一种称为趋磁的机制自然地跟随磁力线。这些载体共享由磁场控制和在磁共振图像上被检测的能力。
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