Systemic Lupus Erythematosus as a Risk Factor for Cervical Cancer and its Precursor Conditions: Assessment Using Pap Smear and Histopathology

M. Gobran, Soheir El-Ghoneimey, S. Ibrahim, Sabah Mohamedhanafy
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Abstract

Background Cancer of the cervix is a common cause of malignancy. Its association with systemic lupus erythematosus (SLE) is debatable. Objective Early detection of cervical pre-neoplastic lesion in SLE patients. Method A case control study was performed on 64 SLE group and 64 control group using a colposcopy, pap smear and histopathological examination. Conclusion This study revealed that preneoplastic and neoplastic lesions of the cervix were higher in the SLE group.
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系统性红斑狼疮是宫颈癌及其前体疾病的危险因素:使用巴氏涂片和组织病理学进行评估
宫颈癌是一种常见的恶性肿瘤。它与系统性红斑狼疮(SLE)的关系是有争议的。目的早期发现SLE患者宫颈肿瘤前病变。方法采用阴道镜、子宫颈涂片和组织病理学检查对64例SLE组和64例对照组进行病例对照研究。结论SLE组子宫颈癌前病变和肿瘤病变发生率较高。
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