Overall health-related quality of life of HIV infected and non-infected adults in Jos North Local Government Area, Plateau State

I. Kefas, E. Envuladu, C. Miner, B. Pokop, J. Daboer, M. Chingle, M. Banwat, A. Zoakah
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Abstract

Background: The burden of HIV has effects on Health-related quality of life (HRQOL). HRQOL assessment is an essential tool in understanding the patient perspective of their quality of life. This study aimed to determine and compare the HRQOL of HIV infected and non-infected adults in Jos North, Plateau State. Method: This was a comparative cross-sectional study conducted in Jos North LGA between January-March 2018. One hundred and seventy-eight of HIV infected and non-infected adults who met the inclusion criteria were selected using a multistage sampling technique. We used a WHOQOL-HIV Bref questionnaire to collect information. We calculated the difference in domain mean score using student t-test and determine factors associated with HRQOL using Chi-square test and logistic regressions at the 5 % level of significance. Statistical analysis was carried out using SPSS version 23.0. Results: The mean ages of HIV infected and non-infected respondents were 38 ± 9 and 35 ± 10 years, respectively. The overall HRQOL mean score for HIV infected was 3.98 ± 0.70 and 4.06 ± 0.60 for non- infected adults, and this was comparative (P = 0.223). In all the domains, the HRQOL mean scores were significantly different between the HIV infected and non-infected except physical domain (P = 0.962). The odds of good HRQOL was higher among those with tertiary education [aOR:8.33; 95%CI: 2.4–29.3] and those employed [aOR:2.34; 95%CI: 1.1–5.2] among HIV infected respondents. Conclusions: This study showed that the overall HRQOL of HIV infected and non-infected adults were similar in Jos North LGA. However, there was a significant difference in all the domains except for physical domain.
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高原州乔斯北部地方政府区艾滋病毒感染者和未感染者的总体健康相关生活质量
背景:HIV负担对健康相关生活质量(HRQOL)有影响。HRQOL评估是了解患者对其生活质量看法的重要工具。本研究旨在确定和比较高原州Jos North HIV感染者和未感染者的HRQOL。方法:这是一项比较横断面研究,于2018年1月至3月在Jos North LGA进行。采用多阶段抽样技术,选择了178名符合纳入标准的艾滋病毒感染者和非感染者。我们使用WHOQOL-HIV简短问卷收集信息。我们使用学生t检验计算域平均得分的差异,并使用卡方检验和5%显著性水平的logistic回归确定与HRQOL相关的因素。采用SPSS 23.0版本进行统计分析。结果:HIV感染者和非感染者的平均年龄分别为38±9岁和35±10岁。HIV感染者的HRQOL平均评分为3.98±0.70,未感染者的HRQOL平均评分为4.06±0.60,两组比较差异有统计学意义(P = 0.223)。在各领域,除物理领域外,HIV感染者与非HIV感染者的HRQOL平均得分差异均有统计学意义(P = 0.962)。受过高等教育的患者获得良好HRQOL的几率更高[aOR:8.33;95%CI: 2.4-29.3]和在职人员[aOR:2.34;95%CI: 1.1-5.2]。结论:本研究表明,Jos North LGA的HIV感染者和未感染者的总体HRQOL相似。然而,除物理领域外,所有领域均存在显著差异。
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