Effect of Food Allergy among Patients Affected by Delta and Omicron Variants-A Case Study

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Abstract

Background: The variants of SARS-CoV-2 have been affecting people globally since 2020. The Delta variant, mainly in India and the omicron variant in multiple countries since Nov 2021, has infected millions of people; many died out of them. Amongst all factors, food allergy is one factor that also accelerates many infected people’s comorbidities and overall health status during the pandemic. Aims: The study aimed to assess the role of some common food allergies in Delta and Omicron infected people in the Indian population. Methods: The study was designed with 50 covid positive home-isolated patients (out of 62) infected by both the mentioned variants from April 2021 until 15th January 2022. However, they were not severely ill but had comorbidities such as diabetes, obesity, hepatomegaly, etc. After the negative test result, each participant was requested to attend a telephonic interview for 15 minutes. Further, they were offered free online diet consultation considering the fatigue and some allergic symptoms. ATLAS-Ti-9 software was used for the fundamental analysis. Results: Based on their self-referred serological allergy test (SAT), we found that 23 samples of milk (46%), 14 (28%) samples of citrus fruits, 12 (24%) patients were allergic due to mustard oil and other detections too based on the positive interpretation (+ to +++) of specific IgE (IU/ml). The patients were facing type-1 hypersensitivity but no other severe allergic issues. Conclusions: Food allergy accelerated respiratory syndromes and comorbidities, mainly among the infected (Delta and Omicron) patients who could also have a high chance of hypersensitivity due to some common ingesting allergens.
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Delta和Omicron变异对患者食物过敏的影响——一个案例研究
背景:自2020年以来,SARS-CoV-2变体一直在全球范围内影响人类。自2021年11月以来,主要在印度和多个国家出现的Delta型和ommicron型已经感染了数百万人;许多人因此而死。在所有因素中,食物过敏是在大流行期间加速许多感染者的合并症和整体健康状况的一个因素。目的:本研究旨在评估一些常见食物过敏在印度三角洲和欧米克隆感染人群中的作用。方法:在2021年4月至2022年1月15日期间,该研究设计了50名covid阳性家庭隔离患者(来自62名患者),感染了上述两种变体。然而,他们的病情并不严重,但有合并症,如糖尿病、肥胖、肝肿大等。在测试结果为阴性后,每位参与者被要求参加15分钟的电话访谈。此外,考虑到疲劳和一些过敏症状,他们还获得了免费的在线饮食咨询。采用ATLAS-Ti-9软件进行基本分析。结果:基于自检血清过敏试验(SAT),我们发现牛奶23例(46%),柑橘类水果14例(28%),芥末油过敏12例(24%),其他检测也基于特异性IgE (IU/ml)阳性解释(+ ~ +++)。这些患者都有1型超敏反应,但没有其他严重的过敏问题。结论:食物过敏加速呼吸道综合征和合并症,主要发生在感染(Delta和Omicron)的患者中,由于摄入一些常见的过敏原,这些患者也有很高的机会发生超敏反应。
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