{"title":"Research progress of heme oxygenase-1 and chronic obstructive pulmonary disease","authors":"Weixia Li, Jiaqiang Zhang","doi":"10.3760/CMA.J.ISSN.1673-436X.2020.02.007","DOIUrl":null,"url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is a preventable and treatable respiratory disease characterized by persistent airflow limitation.Its mechanism has not yet been fully clarified.In recent years, many studies have shown that oxidative stress and gene polymorphism play a very important role in its development.Heme oxygenase-1 (HO-1) is an important oxygen reductase in the body and is closely related to COPD.This article reviews the relationship between the occurrence, development, treatment and prognosis of HO-1 and COPD, in order to provide new ideas for the diagnosis, treatment and management of COPD. \n \n \nKey words: \nPulmonary disease, chronic obstructive; Genes, duplicate; Heme oxygenase-1","PeriodicalId":10004,"journal":{"name":"Chinese Journal of Asthma","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Asthma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2020.02.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable respiratory disease characterized by persistent airflow limitation.Its mechanism has not yet been fully clarified.In recent years, many studies have shown that oxidative stress and gene polymorphism play a very important role in its development.Heme oxygenase-1 (HO-1) is an important oxygen reductase in the body and is closely related to COPD.This article reviews the relationship between the occurrence, development, treatment and prognosis of HO-1 and COPD, in order to provide new ideas for the diagnosis, treatment and management of COPD.
Key words:
Pulmonary disease, chronic obstructive; Genes, duplicate; Heme oxygenase-1
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