Evaluation of antioxidant potential and antimicrobial activity of successive extracts of Pimpinella tirupatiensis

Journal of Pharmacy Research Pub Date : 2013-09-01 DOI:10.1016/j.jopr.2013.08.025

G. Tharun , Pavan Kumar Pindi

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引用次数: 13

Abstract

Background

An increasing demand for natural additives has shifted the attention from synthetic to natural antioxidants. As leafy vegetables are found to be good source of antioxidants and the present study is to examine the antioxidant potential and antimicrobial activity of leaf extracts of Pimpinella tirupatiensis.

Methods

Antioxidant potential of leaves of P. tirupatiensis was studied using different methods like DPPH, nitric oxide, hydrogen peroxide scavenging activity. Reducing power and antimicrobial activity was estimated by using both gram positive and gram negative microorganisms by using DMF as solvent.

Results

The aqueous extracts showed maximum scavenging activity of DPPH followed by nitric oxide, hydrogen peroxide and reducing power respectively. Benzene and alcoholic extract showed maximum antimicrobial activity.

Conclusion

Substantial amounts of antioxidants including vitamins C and E, carotenoids, flavonoids, phenols and tannins etc. can be utilized to scavenge the excess free radicals from the body.

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tirupatensis连续提取物的抗氧化活性及抑菌活性评价

随着对天然添加剂需求的不断增长，人们的注意力从合成抗氧化剂转向了天然抗氧化剂。由于叶类蔬菜是抗氧化剂的良好来源，本研究旨在研究提鲁帕提叶提取物的抗氧化潜力和抗菌活性。方法采用DPPH、一氧化氮、过氧化氢清除活性等不同方法研究红参叶片的抗氧化能力。以DMF为溶剂，对革兰氏阳性微生物和革兰氏阴性微生物的还原力和抑菌活性进行了评价。结果水提物对DPPH的清除能力最强，其次是一氧化氮、过氧化氢和还原力。苯和醇提取物的抑菌活性最高。结论维生素C、E、类胡萝卜素、黄酮类、酚类、单宁类等抗氧化剂可清除体内多余的自由基。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Pharmacy Research

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