Prolactin as a Factor Influencing the Course of a New Coronavirus Infection: a Literary Review

Abstract

Aim: to present the likely pathophysiological mechanisms of hyperprolactinemia development in patients with a new coronavirus infection, as well as to present the results of clinical studies available at the time of writing the review to assess the contribution of hyperprolactinemia to the severity of the coronavirus infection. Key points: hyperprolactinemia is considered as a negative factor contributing to a more severe course of coronavirus infection in different groups of patients. The more severe course of a covid infection is based on the development of inflammatory processes that increase with an increased level of prolactin in the blood. Conclusion. The authors of most research papers report that experimental, clinical trials and clinical studies are needed to confirm the inflammatory and/or anti-inflammatory role of prolactin in the setting of coronavirus infection. Keywords: prolactin, hyperprolactinemia, new coronavirus infection.