Electrochemical Methods for the Detection of Antimicrobial Resistance and Multi-Drug Resistance Bacteria

Fatma Dogan Guzel
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Abstract

Accurate diagnosis of bacteria is one of the most important stages of the definitive treatment of bacterial infections. However, due to the Antibiotic Resistance (AR) that has recently emerged in bacteria, not only the diagnosis of bacteria but also the determination of the antibiotic resistance has become extremely important. For the determination of AR of bacteria, classical microbiological and biochemistry methods are already applied. However, these methods have many disadvantages in terms of cost and time. With advances in technology as well as molecular biology, a new era has emerged for the accurate determination of AR in bacteria as well. For example, electrochemical methods have been developed recently for the label-free diagnosis of both bacteria and their AR. In this we focus on the issues regarding AR of bacteria and their diagnostic significance. Herein, we also focused on the electrochemical method used for the diagnosis of bacteria and AR.
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抗菌药物耐药及多重耐药细菌的电化学检测方法
细菌的准确诊断是最终治疗细菌感染的最重要阶段之一。然而,由于近年来细菌中出现的抗生素耐药性(Antibiotic Resistance, AR),不仅对细菌进行诊断,而且对抗生素耐药性的测定也变得极为重要。对于细菌的AR测定,经典的微生物学和生物化学方法已经得到了应用。然而,这些方法在成本和时间方面有许多缺点。随着技术和分子生物学的进步,细菌中AR的精确测定也进入了一个新的时代。例如,最近已经开发了用于细菌及其AR的无标签诊断的电化学方法。在本文中,我们重点讨论了有关细菌AR及其诊断意义的问题。在此,我们还重点研究了用于细菌和AR诊断的电化学方法。
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