Recent review on 1,3-thiazole derivatives as therapeutic targeted for anticancer activity

Shweta Mishra, Adarsh Sahu
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Abstract

In the past two decades, targeted cancer therapy has emerged as a novel class of anticancer therapeutics besides traditional chemotherapy, surgery, and radiotherapy. There is an extensive variety of anticancer drugs in the market, and several compounds are in various stages of clinical trials. Many studies indicate that these cytotoxic molecules are also associated with various types of toxicity and contrary side effects; thus, researchers all over the world are working to develop more effective and safer anticancer drugs. 1,3-thiazole derivatives have recently been identified as a novel class of cancer chemotherapeutic agents with promising activity against various tumors. In this review, we have systematically summarized and highlighted the latest developments in 1,3-thiazole derivative for anticancer activity.
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1,3-噻唑衍生物抗癌活性研究进展
在过去的二十年中,靶向癌症治疗已经成为继传统的化疗、手术和放疗之后的一种新型抗癌治疗方法。市场上的抗癌药物种类繁多,有几种化合物正处于临床试验的不同阶段。许多研究表明,这些细胞毒性分子还与各种类型的毒性和相反的副作用有关;因此,全世界的研究人员都在努力开发更有效、更安全的抗癌药物。1,3-噻唑衍生物近年来被认为是一类新的肿瘤化疗药物,对多种肿瘤具有良好的治疗作用。本文系统地综述了1,3-噻唑衍生物抗癌活性的最新研究进展。
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