Clinical and laboratory features of acute respiratory viral infections in hospitalized children

Abstract

The aim of the study was to study the clinical and laboratory features of acute respiratory viral infections in hospitalized children.The analysis of medical records of 623 patients admitted to the clinic, aged from 1 month to 16 years 11 months 29 days, was carried out. All patients were diagnosed with ARVI on the basis of clinical symptoms with laboratory confirmation in the study of naso- or oropharyngeal smears by PCR.Three groups of children were identified: with respiratory syncytial (RSV) — 384 children (61,6%), metapneumovirus — 142 (22,8%) and bocavirus — 97 (15,6%) infections. It has been established that in the general structure of acute respiratory viral infections in hospitalized children, RSV and rhinovirus are the leading pathogens — 28,8—48,6% and 22,1—41,3%, respectively, depending on the calendar year. The main clinical form was acute bronchitis in 80,5% of cases of confirmed infection, with RS-viral etiology in 79,5% (n = 287) of cases, with metapneumo- and bocavirus infections in 85,6% (n = 95) and 77,8% (n = 56) of children, respectively. Bronchiolitis was characteristic of RSV infection in 10,5% of cases (n = 38). From 10 to 19,4% of cases, the course of these viral infections was complicated by the development of pneumonia.