Alliance of two pandemics: COVID-19 and diabetes mellitus

Dmitriy V. Kovalevskiy
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Abstract

Objective: to study the features of the course of viral pneumonia in patients with diabetes mellitus. Materials and methods. A random sampling method was used to conduct a retrospective analysis of 300 archival medical records of inpatients with laboratory-instrumentally confirmed COVID-associated pneumonia for the period 2020-2022. Results. As a result of the study, two groups were formed - the main and control. The main group included 150 patients diagnosed with diabetes mellitus; the control group consisted of 150 patients without diabetes mellitus. The average number of bed-days spent by the main group in the hospital was 12.4 days, the control group - 10.5 days (р˂0.001). Significantly more often, the main group of patients is diagnosed with a serious condition at the time of hospitalization, as well as unilateral localization of the pathological process in the lungs. Conclusion. In patients with diabetes mellitus and pneumonia caused by a new coronavirus infection, a dependence of the volume fraction of lung tissue damage on the level of hyperglycemia was revealed. In patients with DM, anticoagulant therapy was carried out longer during inpatient treatment, combinations of several groups of antibacterial drugs were used more often, and the starting dose of glucocorticosteroids was also higher.
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两大流行病联盟:COVID-19和糖尿病
目的:探讨糖尿病合并病毒性肺炎的病程特点。材料和方法。采用随机抽样方法,对2020-2022年300例仪器检测确诊的新型冠状病毒相关肺炎住院患者病历进行回顾性分析。结果。研究结果形成了两组——主要组和对照组。主要组为糖尿病患者150例;对照组为无糖尿病患者150例。主组患者在医院的平均住院日为12.4天,对照组为10.5天(p < 0.001)。更常见的是,主要患者在住院时被诊断为病情严重,以及肺部病变过程的单侧局限性。结论。在糖尿病合并新型冠状病毒感染的肺炎患者中,发现肺组织损伤体积分数与高血糖水平的相关性。糖尿病患者住院期间抗凝治疗时间较长,多组抗菌药物联合使用较多,糖皮质激素起始剂量也较高。
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