Arteriovenous fistula, pulmonary hypertension, and tricuspid dysfunction in renal transplant recipients. A possible solution

R. C. Cruz Abascal, José Ignacio Ramírez Gómez, Carlos Genaro Gutiérrez Gutiérrez, Lisbel Pérez Delgado
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Abstract

Introduction: Cardiovascular dysfunction is the first cause of death in patients with chronic kidney disease. Methods: Observational, longitudinal and prospective study, which included 58 patients with functioning renal transplant who were studied different echocardiographic variables, before and six months after the closure of the arteriovenous fistula. Results: The average age was 46.62 years and the most frequent was male 30 (51.72%). The flow of angioaccesses at the wrist level was demonstrated in 28 patients (45.9%) with evidence of regression of mean pulmonary artery pressure from 25.56 to 19.58 mmHg (p=0.002), more connoted for those of intermediate flow; 14. Also, the area of tricuspid insufficiency was greater for that group; from 3.15 to 1.96 cm2 (p=0.001). The pattern of mild dysfunction was observed in 38 patients (62.3%) prior to closure. Subsequent to this 27; (51.9%), exhibited minimal valvular insufficiency and 9 individuals (14.9%) did not show any degree of valvular dysfunction. Conclusions: Closure of the arteriovenous fistula in patients with functioning renal transplantation contributed to decrease the risk of pulmonary hypertension and progression of tricuspid valve dysfunction.
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肾移植受者的动静脉瘘、肺动脉高压和三尖瓣功能障碍。一个可能的解决方案
简介:心血管功能障碍是慢性肾病患者死亡的首要原因。方法:观察性、纵向和前瞻性研究,纳入58例功能性肾移植患者,研究动静脉瘘关闭前和关闭后6个月的不同超声心动图变量。结果:患者平均年龄46.62岁,以30岁男性居多,占51.72%。28例患者(45.9%)出现手腕水平的血管通路血流,平均肺动脉压从25.56降至19.58 mmHg (p=0.002),中间血流的患者更为明显;14. 另外,三尖瓣功能不全的面积也更大;从3.15到1.96 cm2 (p=0.001)。38例患者(62.3%)在关闭前出现轻度功能障碍。在这之后27;(51.9%)表现出轻微的瓣膜功能不全,9人(14.9%)没有表现出任何程度的瓣膜功能障碍。结论:功能肾移植患者关闭动静脉瘘有助于降低肺动脉高压和三尖瓣功能障碍进展的风险。
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审稿时长
11 weeks
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