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A Cross-Sectional Study of Etiology and Clinico-Hematological Profile of Pancytopenia in Children at Tertiary Care Centre in Western India 印度西部三级医疗中心儿童全血细胞减少症病因和临床血液学特征的横断面研究
Pub Date : 2024-02-22 DOI: 10.25259/ijrsms-2021-12-2
Anjali Kale, T. Idhate, Rishivardhan Reddy
Pancytopenia is one of the most common blood disorders observed in routine clinical practice. There are few studies analyzing pancytopenia in Indian scenarios. This cross-sectional study is aimed to identify the cause of pancytopenia and analyze the clinico-hematological characteristics of children with pancytopenia in Western India. So this study was conducted to evaluate clinico-hematological profile of children presenting with pancytopenia and to determine the etiology of pancytopenia in Western India.This two-year descriptive cross-sectional study was conducted in a tertiary care referral hospital. All children with pancytopenia, ranging in age from 1 month to 18 years, were enrolled in the study. A thorough history was taken, as well as general and systemic examination findings, hematological parameters, and bone marrow examination findings were recorded.The age group of enrolled patients ranged from 1 month to 18 years in the 130 cases evaluated (63 males and 67 females), while the mean age was 9.8 years. Fever was the most prevalent symptom (n = 111, 85.40%), followed by generalized weakness and weight loss. Pallor was the most common physical manifestation, followed by knuckle pigmentation, hepatomegaly, and splenomegaly. Study results concluded that the most common cause of pancytopenia was megaloblastic anemia, followed by acute leukemia, aplastic anemia, and infections. Megaloblastic anemia can be distinguished from other causes of pancytopenia based on dietary habits, hematological parameters and serum B12 levels, potentially obviating the necessity for a bone marrow test in most pancytopenia patients.In pancytopenia patients, detailed initial hematological investigations, including bone marrow examination, are beneficial for correct diagnosis. Although megaloblastic anemia is the most prevalent cause, other factors to examine include aplastic anemia, leukemia, Hemophagocytic Lymphohistiocytosis (HLH), hypersplenism, Systemic Lupus Erythematosus (SLE), and viral infections. When a complete history, clinical examination, and baseline hematological parameters are adequately assessed, bone marrow examination can be avoided in most pancytopenia patients.
全血细胞减少症是常规临床实践中最常见的血液疾病之一。分析印度全血细胞减少症的研究很少。这项横断面研究旨在确定全血细胞减少症的病因,并分析印度西部全血细胞减少症患儿的临床血液学特征。这项为期两年的描述性横断面研究在一家三级护理转诊医院进行。这项为期两年的描述性横断面研究是在一家三级护理转诊医院进行的。所有患有全血细胞减少症的儿童均被纳入研究,年龄从 1 个月到 18 岁不等。在接受评估的 130 例患者中,年龄从 1 个月到 18 岁不等(男 63 例,女 67 例),平均年龄为 9.8 岁。发热是最常见的症状(111 人,占 85.40%),其次是全身乏力和体重减轻。苍白是最常见的体征,其次是指关节色素沉着、肝肿大和脾肿大。研究结果表明,导致全血细胞减少最常见的原因是巨幼细胞性贫血,其次是急性白血病、再生障碍性贫血和感染。巨幼细胞性贫血可根据饮食习惯、血液学参数和血清 B12 水平与其他原因导致的全血细胞减少相鉴别,因此大多数全血细胞减少患者无需进行骨髓检查。虽然巨幼细胞性贫血是最常见的病因,但其他需要检查的因素包括再生障碍性贫血、白血病、嗜血细胞淋巴组织细胞增多症(HLH)、脾功能亢进、系统性红斑狼疮(SLE)和病毒感染。如果对完整的病史、临床检查和基线血液学参数进行了充分评估,大多数全血细胞减少症患者都可以避免骨髓检查。
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引用次数: 0
Effectiveness of Virtual Reality Environment for Post-Operative Pain Management 虚拟现实环境对术后疼痛管理的效果
Pub Date : 2024-02-20 DOI: 10.25259/ijrsms_29_2023
Srinidhi Thippabathuni, Venkata Anil Chandra Dronamraju, Himavathy Kodandarao Gara, Dharma Rao Vanamali
The imperative need of post-operative period is effective pain management. Virtual reality (VR) causes psychological distraction from pain stimuli, and thus may cause pain alleviation. The study was undertaken to determine the effectiveness of VR distraction on post-operative pain and experience of VR sessions among the patients.A hospital-based interventional study was conducted for a period of two months with the objectives to estimate changes in post-operative pain intensity after VR session as well as to analyze experience related to VR interventions. It comprised patients of either gender undergoing surgery and with 1–3 days of hospitalization, who were randomized into two groups (age and gender matched). The control group was kept on standard post-operative pain management. The interventional group was subjected to VR exposure in addition to standard care therapy. The Numerical Rating Scale (NRS) scores were obtained twice post-operatively in subsequent days. I-group presence questionnaire (IPQ) responses were obtained after the VR session.Both control and interventional groups had 25 participants each for analysis. In both the groups, majority were given bupivacaine for anesthesia and combination of paracetamol and diclofenac for post-operative analgesia. The NRS scores of both groups obtained post-operatively on standard therapy without VR intervention did not show any significant difference. However, the post-VR-sessions’ NRS scores showed significant reduction as compared to pre-session scores among the participants of the interventional group. The responses obtained via IPQ revealed acceptance for the features of realism, engagement, and presence during VR intervention. Majority confirmed their willingness to undergo VR sessions in future.VR session helped in significant reduction of pain perception as VR simulation diverted considerable attention away from the pain. Majority expressed positive inclination for utilization of VR in comprehensive patient care.
术后的当务之急是有效控制疼痛。虚拟现实(VR)可以从心理上分散疼痛刺激,从而减轻疼痛。这项研究旨在确定 VR 分散注意力对术后疼痛的影响,以及患者对 VR 体验的感受。这项以医院为基础的干预研究为期两个月,目的是估计 VR 体验后术后疼痛强度的变化,并分析与 VR 干预相关的体验。研究对象包括接受手术并住院 1-3 天的男女患者,他们被随机分为两组(年龄和性别匹配)。对照组接受标准的术后疼痛治疗。干预组在接受标准护理治疗的同时,还接受了 VR 体验。术后两天内进行两次数字评定量表(NRS)评分。对照组和干预组各有 25 人参加分析。对照组和干预组各有 25 名参与者进行分析。两组中的大多数人都使用布比卡因进行麻醉,并在术后联合使用扑热息痛和双氯芬酸进行镇痛。两组患者术后在未接受 VR 干预的标准疗法中获得的 NRS 评分没有显示出任何显著差异。然而,VR 会话后的 NRS 评分显示,与会话前相比,干预组参与者的 NRS 评分明显下降。通过 IPQ 获得的回答显示,受试者接受 VR 干预过程中的真实感、参与感和临场感。由于 VR 模拟转移了人们对疼痛的大量注意力,因此 VR 课程有助于显著降低疼痛感。大多数人对在病人综合护理中使用 VR 表示了积极的倾向。
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引用次数: 0
A Study of Blood Viscosity and Inflammatory Biomarkers’ Levels in Bilateral Primary Varicose Veins/Reticular Veins as Predictive Markers 将双侧原发性静脉曲张/网状静脉的血液粘度和炎症生物标志物水平作为预测指标的研究
Pub Date : 2024-02-16 DOI: 10.25259/ijrsms_4_2023
Mukul Urvendra Dahiya, Sanjay Singh, Saurabh Singh, Santosh Kumar Singh, Varsha Kumar
Cross-sectional data was collected for a period of 1 year to assess the biomarkers of inflammation, and blood viscosity as predictive markers in patients with primary bilateral varicose veins or reticular veins that might progress to varicose veins.A sample of 40 participants, 20 controls and 20 patients aged 18–65 years falling under the reticular veins and symptomatic varicose veins (C1, 2s), primary etiology (Ep), superficial veins (As), reflux pathology (Pr) categories of Clinical, etiologic, anatomic, Pathophysiologic (CEAP) classification with the exception of telangiectatic veins, were included in the study. Blood viscosity was measured using a Capillary Viscometer. Evaluated inflammatory markers were tissue Plasminogen Activator (tPA), Plasminogen Activator Inhibitor-1 (PAI-1), and fibrinogen. Analysis was done using Statistical Package for the Social Sciences (SPSS) software and Chi-square, Fisher’s, Bonferroni, and Analysis of Variance (ANOVA) tests were applied.There was a statistically insignificant relationship between occupation and different study groups. Standing hours and serum fibrinogen levels had a significant difference in different study groups. Serum tPA, Serum PAI-1, and blood viscosity had an insignificant difference between different study groups. It was revealed that the pairwise group comparisons of study group C2 vs. control group C0, study group C1 vs. control group C0 and study group C2 vs. study group C1, and study group C2 vs. control group C0 each were significantly different pairwise.Blood viscosity, tPA and PAI-1 cannot be used as predictive markers in patients with bilateral (B/L) primary varicose veins/reticular veins. Serum fibrinogen levels can be used as predictive markers for the development of B/L primary varicose veins and in our particular study with a predictive range of 189.4–327.9 mg/dL but not for B/L reticular veins. Prolonged standing, irrespective of the occupation of the patient, is associated with the development of B/L reticular veins and B/L varicose veins.
我们收集了为期一年的横断面数据,以评估作为原发性双侧静脉曲张或可能发展为静脉曲张的网状静脉患者的预测指标的炎症生物标志物和血液粘度。研究共纳入了 40 名参与者,其中 20 名是对照组,20 名是 18-65 岁的患者,他们都属于网状静脉和症状性静脉曲张(C1、2s)、原发性病因(Ep)、浅表静脉(As)、临床、病因、解剖、病理生理学(CEAP)分类中的反流病理(Pr)类别,但毛细血管扩张静脉除外。使用毛细管粘度计测量血液粘度。评估的炎症指标包括组织浆蛋白酶原激活剂(tPA)、浆蛋白酶原激活剂抑制剂-1(PAI-1)和纤维蛋白原。采用社会科学统计软件包(SPSS)进行分析,并进行了卡方检验、费雪检验、Bonferroni 检验和方差分析(ANOVA)。不同研究组的站立时间和血清纤维蛋白原水平有显著差异。血清 tPA、血清 PAI-1 和血液粘度在不同研究组之间的差异不显著。结果显示,研究组 C2 与对照组 C0、研究组 C1 与对照组 C0、研究组 C2 与研究组 C1、研究组 C2 与对照组 C0 的配对组比较均有显著差异。血清纤维蛋白原水平可作为双侧(B/L)原发性静脉曲张的预测指标,在我们的研究中,预测范围为 189.4-327.9 mg/dL,但不能作为双侧(B/L)网状静脉的预测指标。无论患者从事何种职业,长时间站立都与 B/L 网状静脉和 B/L 静脉曲张的发生有关。
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引用次数: 0
A Study to Assess the Burden of Hematological Malignancies at a Tertiary Care Center 一项评估三级医疗中心血液恶性肿瘤负担的研究
Pub Date : 2024-02-12 DOI: 10.25259/ijrsms_13_2023
Vinayak Pai, Pramod Gite, Kavita Joshi, Alhad Mulkalwar, Vikram Kate
Hematological malignancies place a significant financial and medical burden on the affected patients. Well-equipped oncology centers providing healthcare for these patients are also sparse. By studying the epidemiology of those diagnosed with hematological malignancies, it can be correlated with the outcomes and compared with global and national trends. This will allow healthcare decision-makers at all levels to make informed decisions, while allocating resources to combat hematological malignancies. This study is aimed at understanding the pattern of various hematological malignancies presenting at a tertiary care center including their clinical profile, risk factors, etiology and presentation.This was an observational prospective study conducted in King Edward Memorial Hospital, Mumbai, India. Patients aged 12 years and above suffering from hematological malignancies were recruited from the medical wards. The history and systemic examination findings were recorded from patients’ records. The patients were treated as per the discretion of the treating physician and all investigations advised by the treating physician were noted in the respective case record forms.The maximum cases were from the age group 36–50 years, i.e., 32 in number (40%), followed by the age group 51–65 years (25%). A greater number of male patients were encountered than female ones (67.5% vs 32.5%). Most of the patients were unskilled laborers followed by semi-skilled workers. Pesticide exposure was the commonest etiological factor reported in 16 (20%) patients, followed by exposure to silica that was reported in nine patients (11.25%).The common age group to encounter hematological malignancies in patients is 36–50 years, being more prevalent among males. History of exposure to risk factors such as pesticides is commonly seen. Factors such as age and family history do not correlate with the outcome. Females tend to have a better outcome than males.
血液恶性肿瘤给患者带来了沉重的经济和医疗负担。为这些患者提供医疗服务的设备完善的肿瘤中心也非常稀少。通过研究血液恶性肿瘤患者的流行病学,可以将其与治疗结果联系起来,并与全球和全国的趋势进行比较。这将使各级医疗决策者在分配防治血液恶性肿瘤的资源时做出明智的决定。这项研究旨在了解在一家三级医疗中心就诊的各种血液恶性肿瘤的发病模式,包括其临床概况、风险因素、病因和发病表现。该研究在印度孟买爱德华国王纪念医院进行,从内科病房招募了 12 岁及以上的血液恶性肿瘤患者。病史和系统检查结果均记录在患者病历中。患者的治疗由主治医生决定,主治医生建议的所有检查均记录在相应的病例记录表中。病例最多的年龄组为 36-50 岁,即 32 例(40%),其次是 51-65 岁年龄组(25%)。男性患者多于女性患者(67.5% 对 32.5%)。大多数患者是非熟练工人,其次是半熟练工人。据报告,接触杀虫剂是最常见的致病因素,有 16 名患者(20%)患此病,其次是接触二氧化硅,有 9 名患者(11.25%)患此病。有杀虫剂等危险因素接触史的患者很常见。年龄和家族史等因素与预后无关。女性的预后往往好于男性。
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引用次数: 0
A Study to Assess the Burden of Hematological Malignancies at a Tertiary Care Center 一项评估三级医疗中心血液恶性肿瘤负担的研究
Pub Date : 2024-02-12 DOI: 10.25259/ijrsms_13_2023
Vinayak Pai, Pramod Gite, Kavita Joshi, Alhad Mulkalwar, Vikram Kate
Hematological malignancies place a significant financial and medical burden on the affected patients. Well-equipped oncology centers providing healthcare for these patients are also sparse. By studying the epidemiology of those diagnosed with hematological malignancies, it can be correlated with the outcomes and compared with global and national trends. This will allow healthcare decision-makers at all levels to make informed decisions, while allocating resources to combat hematological malignancies. This study is aimed at understanding the pattern of various hematological malignancies presenting at a tertiary care center including their clinical profile, risk factors, etiology and presentation.This was an observational prospective study conducted in King Edward Memorial Hospital, Mumbai, India. Patients aged 12 years and above suffering from hematological malignancies were recruited from the medical wards. The history and systemic examination findings were recorded from patients’ records. The patients were treated as per the discretion of the treating physician and all investigations advised by the treating physician were noted in the respective case record forms.The maximum cases were from the age group 36–50 years, i.e., 32 in number (40%), followed by the age group 51–65 years (25%). A greater number of male patients were encountered than female ones (67.5% vs 32.5%). Most of the patients were unskilled laborers followed by semi-skilled workers. Pesticide exposure was the commonest etiological factor reported in 16 (20%) patients, followed by exposure to silica that was reported in nine patients (11.25%).The common age group to encounter hematological malignancies in patients is 36–50 years, being more prevalent among males. History of exposure to risk factors such as pesticides is commonly seen. Factors such as age and family history do not correlate with the outcome. Females tend to have a better outcome than males.
血液恶性肿瘤给患者带来了沉重的经济和医疗负担。为这些患者提供医疗服务的设备完善的肿瘤中心也非常稀少。通过研究血液恶性肿瘤患者的流行病学,可以将其与治疗结果联系起来,并与全球和全国的趋势进行比较。这将使各级医疗决策者在分配防治血液恶性肿瘤的资源时做出明智的决定。这项研究旨在了解在一家三级医疗中心就诊的各种血液恶性肿瘤的发病模式,包括其临床概况、风险因素、病因和发病表现。该研究在印度孟买爱德华国王纪念医院进行,从内科病房招募了 12 岁及以上的血液恶性肿瘤患者。病史和系统检查结果均记录在患者病历中。患者的治疗由主治医生决定,主治医生建议的所有检查均记录在相应的病例记录表中。病例最多的年龄组为 36-50 岁,即 32 例(40%),其次是 51-65 岁年龄组(25%)。男性患者多于女性患者(67.5% 对 32.5%)。大多数患者是非熟练工人,其次是半熟练工人。据报告,接触杀虫剂是最常见的致病因素,有 16 名患者(20%)患此病,其次是接触二氧化硅,有 9 名患者(11.25%)患此病。有杀虫剂等危险因素接触史的患者很常见。年龄和家族史等因素与预后无关。女性的预后往往好于男性。
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引用次数: 0
Incidence and Demographic Characteristics of Patients with Post Cardiac Surgery Arrhythmias: A Single Center Retrospective Study 心脏手术后心律失常患者的发病率和人口统计学特征:单中心回顾性研究
Pub Date : 2024-02-06 DOI: 10.25259/ijrsms_30_2023
Adel Khalifa Hamad, Tarique Shahzad Chachar, Ali J Al Hashli, Babur Ikram, Khalifa Abdulrahman Yousif, Manar Al Suwaidi, Habib Al Tareif, Zaid Arekat, Abdulwahab Al Khalifa
Arrhythmias are a common complication following cardiac surgery, and can significantly affect patients’ outcomes. In some cases, post-operative arrhythmias may lead to hemodynamic instability, congestive heart failure, or even sudden cardiac death. Various types of cardiac surgery result in varying rates of post-operative arrhythmias, with more complex procedures causing higher rates. Risk factors for post-operative arrhythmias include advanced age, pre-existing cardiovascular disease, electrolyte imbalances, and the type of cardiac surgery. In this study, we aim to determine the incidence and demographic characteristics of patients who underwent cardiac surgery from November 15, 2020, till November 30, 2021, in a tertiary center in the Kingdom of Bahrain.All adult patients (18 years or older) who were booked for cardiac surgery during the study period were included. Patients with pre-existing documented arrhythmias were excluded from the study. Data was collected from patients’ clinical notes including demographic information (age, sex, and nationality), medical history, comorbidities, type of cardiac surgery, laboratory investigations, and mortality. Descriptive statistics was used to analyze the data, including frequency distributions, means, and standard deviations. Data was collected from patients’ clinical notes including demographic information (age, sex, and nationality), medical history, comorbidities, type of cardiac surgery, laboratory investigations, length of hospital stay, and mortality. Data was collected from patients’ clinical notes including demographic information (age, sex, and nationality), medical history, comorbidities, type of cardiac surgery, laboratory investigations, length of hospital stay, and mortality.A total of 161 patients were enrolled in the study with a mean age of 56.75 ± 1.68 years. Among the total enrolled population, 68.32% were male and 31.68% were female. The majority of patients (61.49%) had undergone urgent surgery. Approximately, half (49.07%) of the patients had coronary artery bypass surgery. Premature ventricular complexes (PVC), atrial fibrillation (AF), junctional rhythm, heart block, and atrial flutter were reported in 30.43%, 29.19%, 11.18%, 9.31%, and 8.07% of patient populations respectively. Pleural effusion (50.31%) and bleeding (19.25%) were common post-surgery complications observed among the patients. The mean oxygen saturation (sO2) of the patients on the day of arrhythmia was 95.67 ± 2.05%. Epinephrine/norepinephrine (71.43%) was the most used inotropic agent used after cardiac surgery.Cardiac surgery is associated with various arrhythmias. The two most common arrhythmias observed in patients after cardiac surgery are premature ventricular contractions and atrial fibrillation.
心律失常是心脏手术后常见的并发症,会严重影响患者的预后。在某些情况下,术后心律失常可能导致血液动力学不稳定、充血性心力衰竭,甚至心脏性猝死。各种类型的心脏手术导致的术后心律失常发生率各不相同,越复杂的手术导致的心律失常发生率越高。术后心律失常的风险因素包括高龄、原有心血管疾病、电解质失衡和心脏手术类型。在这项研究中,我们旨在确定巴林王国一家三级医疗中心 2020 年 11 月 15 日至 2021 年 11 月 30 日期间接受心脏手术的患者的发病率和人口统计学特征。研究对象不包括已有心律失常记录的患者。研究人员从患者的临床记录中收集数据,包括人口统计学信息(年龄、性别和国籍)、病史、合并症、心脏手术类型、实验室检查和死亡率。数据分析采用描述性统计方法,包括频率分布、平均值和标准差。从患者的临床记录中收集数据,包括人口统计学信息(年龄、性别和国籍)、病史、合并症、心脏手术类型、实验室检查、住院时间和死亡率。研究从患者的临床记录中收集数据,包括人口统计学信息(年龄、性别和国籍)、病史、合并症、心脏手术类型、实验室检查、住院时间和死亡率。在所有登记的患者中,68.32%为男性,31.68%为女性。大多数患者(61.49%)接受过紧急手术。大约一半(49.07%)的患者接受过冠状动脉搭桥手术。室性早搏(PVC)、心房颤动(AF)、交界性心律、心脏传导阻滞和心房扑动分别占患者总数的 30.43%、29.19%、11.18%、9.31% 和 8.07%。胸腔积液(50.31%)和出血(19.25%)是常见的术后并发症。心律失常当天患者的平均血氧饱和度(sO2)为 95.67 ± 2.05%。肾上腺素/去甲肾上腺素(71.43%)是心脏手术后使用最多的肌力药物。心脏手术后患者最常见的两种心律失常是室性早搏和心房颤动。
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引用次数: 0
Incidence and Demographic Characteristics of Patients with Post Cardiac Surgery Arrhythmias: A Single Center Retrospective Study 心脏手术后心律失常患者的发病率和人口统计学特征:单中心回顾性研究
Pub Date : 2024-02-06 DOI: 10.25259/ijrsms_30_2023
Adel Khalifa Hamad, Tarique Shahzad Chachar, Ali J Al Hashli, Babur Ikram, Khalifa Abdulrahman Yousif, Manar Al Suwaidi, Habib Al Tareif, Zaid Arekat, Abdulwahab Al Khalifa
Arrhythmias are a common complication following cardiac surgery, and can significantly affect patients’ outcomes. In some cases, post-operative arrhythmias may lead to hemodynamic instability, congestive heart failure, or even sudden cardiac death. Various types of cardiac surgery result in varying rates of post-operative arrhythmias, with more complex procedures causing higher rates. Risk factors for post-operative arrhythmias include advanced age, pre-existing cardiovascular disease, electrolyte imbalances, and the type of cardiac surgery. In this study, we aim to determine the incidence and demographic characteristics of patients who underwent cardiac surgery from November 15, 2020, till November 30, 2021, in a tertiary center in the Kingdom of Bahrain.All adult patients (18 years or older) who were booked for cardiac surgery during the study period were included. Patients with pre-existing documented arrhythmias were excluded from the study. Data was collected from patients’ clinical notes including demographic information (age, sex, and nationality), medical history, comorbidities, type of cardiac surgery, laboratory investigations, and mortality. Descriptive statistics was used to analyze the data, including frequency distributions, means, and standard deviations. Data was collected from patients’ clinical notes including demographic information (age, sex, and nationality), medical history, comorbidities, type of cardiac surgery, laboratory investigations, length of hospital stay, and mortality. Data was collected from patients’ clinical notes including demographic information (age, sex, and nationality), medical history, comorbidities, type of cardiac surgery, laboratory investigations, length of hospital stay, and mortality.A total of 161 patients were enrolled in the study with a mean age of 56.75 ± 1.68 years. Among the total enrolled population, 68.32% were male and 31.68% were female. The majority of patients (61.49%) had undergone urgent surgery. Approximately, half (49.07%) of the patients had coronary artery bypass surgery. Premature ventricular complexes (PVC), atrial fibrillation (AF), junctional rhythm, heart block, and atrial flutter were reported in 30.43%, 29.19%, 11.18%, 9.31%, and 8.07% of patient populations respectively. Pleural effusion (50.31%) and bleeding (19.25%) were common post-surgery complications observed among the patients. The mean oxygen saturation (sO2) of the patients on the day of arrhythmia was 95.67 ± 2.05%. Epinephrine/norepinephrine (71.43%) was the most used inotropic agent used after cardiac surgery.Cardiac surgery is associated with various arrhythmias. The two most common arrhythmias observed in patients after cardiac surgery are premature ventricular contractions and atrial fibrillation.
心律失常是心脏手术后常见的并发症,会严重影响患者的预后。在某些情况下,术后心律失常可能导致血液动力学不稳定、充血性心力衰竭,甚至心脏性猝死。各种类型的心脏手术导致的术后心律失常发生率各不相同,越复杂的手术导致的心律失常发生率越高。术后心律失常的风险因素包括高龄、原有心血管疾病、电解质失衡和心脏手术类型。在这项研究中,我们旨在确定巴林王国一家三级医疗中心 2020 年 11 月 15 日至 2021 年 11 月 30 日期间接受心脏手术的患者的发病率和人口统计学特征。研究对象不包括已有心律失常记录的患者。研究人员从患者的临床记录中收集数据,包括人口统计学信息(年龄、性别和国籍)、病史、合并症、心脏手术类型、实验室检查和死亡率。数据分析采用描述性统计方法,包括频率分布、平均值和标准差。从患者的临床记录中收集数据,包括人口统计学信息(年龄、性别和国籍)、病史、合并症、心脏手术类型、实验室检查、住院时间和死亡率。研究从患者的临床记录中收集数据,包括人口统计学信息(年龄、性别和国籍)、病史、合并症、心脏手术类型、实验室检查、住院时间和死亡率。在所有登记的患者中,68.32%为男性,31.68%为女性。大多数患者(61.49%)接受过紧急手术。大约一半(49.07%)的患者接受过冠状动脉搭桥手术。室性早搏(PVC)、心房颤动(AF)、交界性心律、心脏传导阻滞和心房扑动分别占患者总数的 30.43%、29.19%、11.18%、9.31% 和 8.07%。胸腔积液(50.31%)和出血(19.25%)是常见的术后并发症。心律失常当天患者的平均血氧饱和度(sO2)为 95.67 ± 2.05%。肾上腺素/去甲肾上腺素(71.43%)是心脏手术后使用最多的肌力药物。心脏手术后患者最常见的两种心律失常是室性早搏和心房颤动。
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引用次数: 0
Clinical Evaluation and Management of Varicose Veins of Lower Limb at a Tertiary Care Hospital in India 印度一家三级医院对下肢静脉曲张的临床评估和管理
Pub Date : 2024-01-22 DOI: 10.25259/ijrsms_9_2023
C. Shrikanth, Pradeep Tenginkai, Santosh Nayak K
Varicose veins are defined as dilated, tortuous and elongated veins in the lower limbs. Being one of the most common chronic vascular disorders of the lower limb, the varicose veins affect approximately 10% of the population. If left untreated, the patient may end up with complications like ulceration. The present study is aimed at evaluating the demography, risk factors, clinical features and management of varicose vein patients attending the Department of General Surgery at a tertiary care hospital.This is a prospective observational study conducted at a tertiary care hospital involving patients with lower limb varicose veins. Demographic factors like age, gender, etiology, clinical features, site of incompetence, type of surgical procedure and postoperative complications were studied.Out of 74 patients, majority of them (47.2%) were between 41 and 50 years of age, with a predominance of males (51 cases). Analysis of the history of the patients showed that many were chronic alcoholics (72.9%) and chronic smokers (66.2%). Nearly, 91.8% of them presented with visible dilated veins and pain (60.8%) in the affected limb. The long saphenous vein was greatly involved, and majority of them were managed by saphenofemoral flush ligation + subfascial ligation of perforators (SFFL + SFLP) with minimal postoperative complications.Varicosity of the veins of the lower limb is common in patients with long-standing jobs, chronic alcoholics and smokers. Involvement of the long saphenous vein is observed in majority of the patients. Duplex ultrasound is the most sensitive diagnostic procedure and surgery is the primary modality of the treatment.
静脉曲张是指下肢静脉扩张、迂曲和伸长。作为下肢最常见的慢性血管疾病之一,静脉曲张影响着约10%的人口。如果不及时治疗,患者可能会出现溃疡等并发症。本研究旨在评估一家三级甲等医院普外科就诊的静脉曲张患者的人口统计学、风险因素、临床特征和管理。在 74 名患者中,大多数患者(47.2%)的年龄在 41 岁至 50 岁之间,其中男性居多(51 例)。对患者病史的分析表明,许多患者长期酗酒(72.9%)和长期吸烟(66.2%)。近91.8%的患者有明显的静脉扩张和患肢疼痛(60.8%)。他们中的大多数人都接受了隐股静脉冲洗结扎+筋膜下穿孔结扎术(SFFL + SFLP),术后并发症极少。大多数患者的长隐静脉受累。双相超声波是最敏感的诊断方法,手术是治疗的主要方式。
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引用次数: 0
Acute kidney injury in the burn patient 烧伤患者急性肾损伤
Pub Date : 2023-09-20 DOI: 10.32457/ijmss.v10i3.2168
Jorge Fernando Miño–Bernal, Juan Santiago Serna Trejos, Stefanya Geraldine Bermúdez–Moyano
Introducción: Las quemaduras suponen la cuarta causa de trauma en todo el mundo, usualmente se asocian en gran parte a componente renal, generando un deterioro abrupto de la función renal manifestado en descenso de la tasa de filtrado glomerular como en el balance hídrico del paciente. Objetivo: Presentar una revisión narrativa sobre los aspectos relacionados con el abordaje fisiopatológico, diagnósticos y terapéutico en el paciente quemado con lesión renal aguda. Métodos: Revisión narrativa de artículos relevantes y destacados en el área del manejo del paciente quemado con lesión renal aguda, de diferentes bases de datos como Scopus, Medline, Embase y Google Scholar. Resultados: Los mecanismos fisiopatológicos que conducen al paciente quemado a generar lesión renal aguda han sido ampliamente descritos, asociados principalmente a procesos de rabdomiólisis asociado a condiciones agudas como hipovolemia, entre otras. Conclusiones: Un abordaje optimo en el paciente quemado con compromiso renal agudo, puede mejorar la tasa de sobrevida y rehabilitación de la función renal del paciente, previniendo desenlaces fatales, aumentando la sobrevida de pacientes y las complicaciones asociadas a la misma.
简介:烧伤是世界范围内第四个造成创伤的原因,通常主要与肾脏成分有关,导致肾功能突然恶化,表现为肾小球滤过率下降,如患者的水分平衡。目的:对急性肾损伤烧伤患者的病理生理、诊断和治疗方法进行叙述综述。方法:对Scopus、Medline、Embase和谷歌Scholar等不同数据库中急性肾损伤烧伤患者管理领域的相关和突出文章进行叙述综述。结果:本研究的目的是评估烧伤患者的急性肾损伤与横横肌溶解过程之间的关系,这些过程与低血容量等急性条件有关。结论:对于急性肾功能损害的烧伤患者,最佳的治疗方法可以提高患者的生存率和肾功能康复率,防止致命结局,增加患者的生存率和相关并发症。
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引用次数: 0
Initial antimicrobial therapy and case fatality in patients with community-acquired pneumonia 社区获得性肺炎患者的初始抗菌治疗和病死率
Pub Date : 2023-09-20 DOI: 10.32457/ijmss.v10i3.2273
Luis Alberto Corona Martínez, Iris González Morales, María Caridad Fragoso Marchante
The health importance of community-acquired pneumonia is an unquestionable fact given its relationship with hospital and overall mortality. The objective of the investigation was to evaluate the relationship between selected antimicrobials used in the initial treatment (amoxicillin/sulbactam, cefuroxime, ceftriaxone and cefotaxime) and mortality from pneumonia. An observational study was carried out, with a descriptive design and a population of 1,809 patients with pneumonia hospitalized between 2012 and 2019; the necessary information was obtained from the clinical history. Statistical processing was performed using bivariate and multivariate analysis (logistic regression); the ratio of cross products (odds ratio) and its 95% confidence interval were used as a statistician. Among the results, the following stand out: significantly higher lethality values were found in those treated with cefotaxime (33%) than in those who received amoxicillin/sulbactam (24%, OR 1.6[1.0001;2.6]), as well as in those treated with ceftriaxone (30%) compared with those treated with amoxicillin/sulbactam (24%, OR 1.3[1.05;1.8]) and with cefuroxime (24%, OR 1.3[1.04;1.7]). A higher frequency of patients with extensive pneumonia, of patients in a critical state on admission, and of bedridden occurrence during hospitalization were identified in those treated with cefotaxime. In patients with “moderate pneumonia and high probability of unfavorable outcome”, treatment with ceftriaxone or cefotaxime was associated with death; as well as ceftriaxone treatment for all subjects. It is concluded that the initial treatment with amoxicillin/ sulbactam or cefuroxime was more favorable than the use of third generation cephalosporins. Also in the global analysis, the absence of differences in lethality between those treated with amoxicillin/sulbactam and with cefuroxime was recognized.
鉴于社区获得性肺炎与住院和总死亡率的关系,其对健康的重要性是不容置疑的事实。调查的目的是评估初始治疗中所使用的抗菌药物(阿莫西林/舒巴坦、头孢呋辛、头孢曲松和头孢噻肟)与肺炎死亡率之间的关系。进行了一项观察性研究,采用描述性设计,纳入了2012年至2019年期间住院的1809例肺炎患者;从临床病史中获得必要的信息。采用双变量和多变量分析(逻辑回归)进行统计处理;交叉积比(比值比)及其95%置信区间作为统计量。在这些结果中,以下是值得注意的:头孢噻肟组(33%)的致死率显著高于阿莫西林/舒巴坦组(24%,OR 1.6[1.0001;2.6]),头孢曲松组(30%)的致死率显著高于阿莫西林/舒巴坦组(24%,OR 1.3[1.05;1.8])和头孢呋辛组(24%,OR 1.3[1.04;1.7])。在接受头孢噻肟治疗的患者中,发现广泛性肺炎患者、入院时处于危重状态的患者和住院期间卧床的患者的发生率更高。在“中度肺炎和极有可能出现不良结果”的患者中,使用头孢曲松或头孢噻肟治疗与死亡相关;以及所有受试者的头孢曲松治疗。结论阿莫西林/舒巴坦或头孢呋辛初始治疗比使用第三代头孢菌素更有利。在全球分析中,也认识到用阿莫西林/舒巴坦和用头孢呋辛治疗的人在死亡率方面没有差异。
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引用次数: 0
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International Journal of Recent Surgical and Medical Sciences
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