Nimesulide: Advantages, Perspective Use During the Coronavirus Pandemic

Abstract

Objective of the Review: To discuss the specific properties of Nimesulide and its use in COVID-19. Key Points. A significant advantage of Nimesulide is a very rapid analgesic effect, due to rapid and meal-independent absorption in the gastrointestinal tract, almost complete binding to blood albumin, equally rapid achievement of the maximum concentration both in synovial fluid and blood. Now we have some data on the promising use of Nimesulide for COVID-19 management. Conclusion. An idea that Nimesulide should be among the medicinal products undergoing assessment for the use for COVID-19 management, seems rather rational. Although it is not clear whether such studies will be conducted and what their outcome will be, selection of Nimesulide as one of the primary drugs for pain management and inflammation therapy both by medical professionals and patients is not by chance; it is completely informed and justified. Keywords: Nimesulide, nonsteroidal anti-inflammatory drugs, COVID-19.