Influence of chemical composition of the dental paste on the buffering systems in the mouth and the environmental indicator

S. Gromova, S. A. Kuklina, A. Elikov, O. Smetanina, Sergey B. Petrov
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Abstract

In this paper we consider buffering properties of saliva, which are regulated by a colloidal system. It includes Ca2+ and НPO42- ions, which affect on qualitative characteristics of saliva. The constancy of the pH determines neutralizing and mineralizing capabilities of saliva. The aim of this work was to define influence of toothpaste composition on the pH, salivary buffer systems, and the acid-base balance in the oral cavity. The acid-base disruption results in disbalance in demineralization-remineralization processes. Students of the Dentistry Department of Kirov State Medical University of the Ministry of Health of Russia took part in this research. They were divided into three groups. Each group had been using different products for 28 days. We selected 3 toothpastes of the same manufacturer. These toothpastes contain same ingredients, which by their chemical properties are not able to affect on the pH of the oral fluid and salivary buffer systems accordingly. However, there were distinctive components such as dicalcium phosphate dihydrate, hydroxyapatite, tetrapotassium pyrophosphate, calcium lactate, which increase НРО42- and Ca2+. This fact has a positive effect on maintaining fixity of the phosphate buffer system in the oral cavity. It therefore helps to normalize the pH to a neutral level. The acid-base equilibrium is supported by buffering properties of saliva. It knows that saliva is regulated by the colloidal system including Ca2+ and НPO42- ions. These ions are part of the phosphate buffer system, which affect on qualitative characteristics of saliva. Based on the above, there is dependence between the row of toothpaste ingredients and protein level, hydrogen phosphate ions, calcium ions, and pH values.
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牙膏的化学成分对口腔缓冲系统及环境指标的影响
在本文中,我们考虑了唾液的缓冲特性,这是由胶体系统调节。它包括Ca2+和НPO42-离子,影响唾液的定性特性。pH值的恒定决定了唾液的中和和矿化能力。本研究的目的是确定牙膏成分对口腔pH值、唾液缓冲系统和酸碱平衡的影响。酸碱破坏导致脱矿-再矿过程失衡。俄罗斯卫生部基洛夫国立医科大学牙科系的学生参加了这项研究。他们被分成三组。每组使用不同的产品28天。我们选择了同一厂家的3种牙膏。这些牙膏含有相同的成分,它们的化学性质不会影响口服液和唾液缓冲系统的pH值。然而,有独特的成分,如二水磷酸二钙、羟基磷灰石、焦磷酸四钾、乳酸钙,增加НРО42-和Ca2+。这一事实对维持口腔内磷酸盐缓冲系统的固定性有积极作用。因此,它有助于将pH值正常化到中性水平。酸碱平衡是由唾液的缓冲特性支持的。它知道唾液是由包括Ca2+和НPO42-离子在内的胶体系统调节的。这些离子是磷酸盐缓冲系统的一部分,影响唾液的定性特性。综上所述,牙膏成分与蛋白质水平、磷酸氢离子、钙离子、pH值之间存在依赖关系。
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