Liquid-Based Cytology Compared to Conventional Cytology for Diagnosis of Cervical Intraepithelial Neoplasia: A Single-Center Experience

L. Flores-Hernández, Ramírez-Uribe Rd, Villegas-González Lf, Serrano-Arévalo Ml, Cordoba-Gonzalez, Barquet-Muñoz Sa
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Abstract

Conclusion: Considering no statistically differences in the results and the outlay of LBC, implementation of LBC should be used for molecular-based detection and genotyping when human papillomavirus may offer additional benefits when screening for cervical carcinoma. Introduction: Cervical carcinoma is the fourth most common gynecologic cancer. Screening assays that include the conventional cytology (CC) have a sensitivity and specificity far from optimal; however, liquid-based cytology (LBC) may overcome some limitations. The objective is to compare the screening accuracy of LBC and CC in individuals suspected of having precancerous lesions.
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液基细胞学与常规细胞学诊断宫颈上皮内瘤变的比较:单中心经验
结论:考虑到LBC的结果和费用没有统计学差异,当人乳头瘤病毒可能为宫颈癌筛查提供额外的好处时,LBC的实施应用于基于分子的检测和基因分型。简介:宫颈癌是第四大常见妇科癌症。包括常规细胞学(CC)在内的筛选试验灵敏度和特异性远未达到最佳水平;然而,液体细胞学(LBC)可以克服一些局限性。目的是比较在怀疑有癌前病变的个体中LBC和CC的筛查准确性。
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