Portable continuous glucose monitoring systems with implantable fluorescent hydrogel microfibers

2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS 2013) : Taipei, Taiwan, 20-24 January 2013. IEEE International Conference on Micro Electro Mechanical Systems (26th : 2013 : Taipei, Taiwan) Pub Date : 2013-03-07 DOI:10.1109/MEMSYS.2013.6474439

M. Takahashi, Y. Heo, T. Kawanishi, T. Okitsu, S. Takeuchi

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引用次数: 5

Abstract

We present a portable glucose monitoring system comprised of an implantable fluorescent-hydrogel sensor, wearable photo detector, microcontroller, wireless device and software for transdermal, continuous glucose monitoring. Although we showed the potential of the fluorescent-hydrogel fibers for applying to long-term, implanted glucose monitoring, “true” continuous glucose monitoring with a portable monitoring system has yet to be realized. In the system that we propose here, the calculated glucose values show a good correlation with the actual blood glucose concentrations. The portable device attached to the ear of a rat and measured the fluorescence intensity for three days. Therefore, our system shows the potential for practical, “true,” continuous glucose monitoring.

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可植入荧光水凝胶微纤维的便携式连续血糖监测系统

我们提出了一种便携式血糖监测系统，该系统由植入式荧光水凝胶传感器、可穿戴式光电探测器、微控制器、无线设备和软件组成，用于透皮连续血糖监测。虽然我们展示了荧光水凝胶纤维应用于长期植入式血糖监测的潜力，但“真正的”便携式监测系统的连续血糖监测尚未实现。在我们这里提出的系统中，计算出的葡萄糖值与实际血糖浓度有很好的相关性。该便携式装置附着在大鼠的耳朵上，连续三天测量荧光强度。因此，我们的系统显示了实际、“真实”、连续血糖监测的潜力。

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2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS 2013) : Taipei, Taiwan, 20-24 January 2013. IEEE International Conference on Micro Electro Mechanical Systems (26th : 2013 : Taipei, Taiwan)

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