A Constitutive Framework for the Inelastic Mechanical Behavior of Arteries

G. Holzapfel, T. Gasser
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Abstract

A reliable constitutive model of arterial walls is an essential prerequisite to (i) understand the functions of diseased and non-diseased arteries, to (ii) optimize the design of arterial prostheses, and to (iii) improve diagnostics and therapeutical procedures that are based on mechanical treatments, such as percutaneous transluminal angioplasty (PTA) [1] or bypass surgery. PTA is the most frequent therapeutical intervention worldwide [2] to reduce the severity of atherosclerotic stenoses. It is of great and steadily growing medical, economical and scientific interest [3].
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动脉非弹性力学行为的本构框架
可靠的动脉壁本构模型是以下方面的必要前提:(i)了解病变和非病变动脉的功能,(ii)优化动脉假体的设计,以及(iii)改进基于机械治疗的诊断和治疗程序,如经皮腔内血管成形术(PTA)[1]或搭桥手术。PTA是世界范围内最常用的治疗干预措施[2],可降低动脉粥样硬化性狭窄的严重程度。它在医学、经济和科学方面具有巨大且不断增长的价值[3]。
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