Effect of nanomaterials in catheter related nosocomial infection

Abstract

In the current healthcare environment, nosocomial infection is regarded as one of the most life-threatening infections. Hospitalized patients are exposed to contaminants from a range of sources, including medical staff and other sick people. Bacteria associated biofilm infection spread in central line associated blood infections, catheter-associated urinary tract infection, surgical site infection and ventilator-associated respiratory system. According to WHO reports, nearly 15% of all hospitalized patients suffer from this infection. Patients with indwelling urinary catheters have a higher risk of developing urinary tract infections because biofilm formation bacteria can enter the urinary system directly. Metal based nanoparticles is the most advantageous in prevention of biofilm disruption rather than conventional antibiotics. The creation of engineering tailored nanoparticles may signal a new era in the efficient treatment of nosocomial infection caused by the growth of biofilm over indwelling catheters. Nosocomial infections, Healthcare associated infection, Catheter associated infections, engineering tailored nanoparticles, Biofilm Surface.